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Table 4 Signs of scrapie-affected goats kept for milk collection or monitoring of clinical progression

From: Monitoring of clinical signs in goats with transmissible spongiform encephalopathies

Animal

Days at VLA

Genotype

127-142-211-222-240

Breed

Clinical status & signs at arrival

Clinical status & signs prior to cull

Scrapie positive (LRS only)

G08-1472

37

GIRQP/GIRQP

AN

No signs of TSE (difficult to milk)*

No signs of TSE1,4

G08-1427

86

XIRQP/XIRQP

AN

No signs of TSE

No signs of TSE2,4

G08-1396

107

GIRQS/GIRQP

AN

No signs of TSE

Scrapie (see Fig. 1), pruritic activity on camera recordings2,3

G08-1143

99

GIRQS/GIRQS

AN

Inconclusive (ataxia)

Inconclusive (pruritic behaviour on camera recordings)2-4

G08-1389

107

GIRQP/GIRQP

SA

No signs of TSE

Inconclusive (self-induced scratch reflex, pruritic behaviour and abnormal rising on camera recordings)2,3

G08-1465

38

GIRQP/GMRQP

AN

No signs of TSE (difficult to milk)*

Inconclusive (difficult to milk (kicking)1,4

G08-1430

106

GIRQP/GIRQP

AN

Scrapie (positive scratch test)

Scrapie (see Fig. 1)2,3

Scrapie positive (CNS and LRS)

G08-1451

98

GIRQP/GMRQP

AN

No signs of TSE

Inconclusive (pruritic behaviour and abnormal rising on camera recordings)2-4

G08-1415

98

GIRQS/GMRQP

TG

No signs of TSE

Inconclusive (prefers to stay close to pen, kicking when hind limbs touched, head tremor at times, hair loss on left flank not previously seen, pruritic activity on camera recordings)2-4

G08-1383

99

GIRQS/GMRQP

SA

No signs of TSE

Inconclusive (inconclusive scratch test)2-4

G08-1365

107

GIRQP/GMRQP

SA

No signs of TSE

Inconclusive (inconclusive scratch test)2,3

G08-1475

86

GIRQP/GIRQP

AN

No signs of TSE (difficult to milk)*

Scrapie (see Fig. 1), difficult to milk (kicking)2-4

G08-1373

107

SIRQP/GIRQP

SA

Inconclusive (head and body tremor)

Scrapie (see Fig. 1)2,3

G08-1447

57

GIRQP/GIRQP

AN

Inconclusive (head tremor, nervous on head tests)

Scrapie (see Fig. 1), difficult to milk (kicking, sitting down), pruritic activity on camera recordings2-4

G08-1340

39

GIRQP/GMRQP

AN

Scrapie (positive scratch test, teeth grinding)

No signs of TSE (negative scratch test)1

G08-1460

98

GIRQP/GIRQP

AN

Scrapie (positive scratch test, repeated startle to auditory stimuli)

Scrapie (see Fig. 1)2-4

  1. AN = Anglo-Nubian, SA = Saanen, TG = Toggenburg.
  2. The clinical TSE status on arrival was assessed using the short protocol; for the assessment of the clinical TSE status prior to cull clinical assessments (short1 or long2 protocol), camera recordings3 and behaviour at milking4 were taken into consideration.
  3. * Inconclusive signs if behaviour during milking was included.