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Table 4 Signs of scrapie-affected goats kept for milk collection or monitoring of clinical progression

From: Monitoring of clinical signs in goats with transmissible spongiform encephalopathies

Animal Days at VLA Genotype
127-142-211-222-240
Breed Clinical status & signs at arrival Clinical status & signs prior to cull
Scrapie positive (LRS only)
G08-1472 37 GIRQP/GIRQP AN No signs of TSE (difficult to milk)* No signs of TSE1,4
G08-1427 86 XIRQP/XIRQP AN No signs of TSE No signs of TSE2,4
G08-1396 107 GIRQS/GIRQP AN No signs of TSE Scrapie (see Fig. 1), pruritic activity on camera recordings2,3
G08-1143 99 GIRQS/GIRQS AN Inconclusive (ataxia) Inconclusive (pruritic behaviour on camera recordings)2-4
G08-1389 107 GIRQP/GIRQP SA No signs of TSE Inconclusive (self-induced scratch reflex, pruritic behaviour and abnormal rising on camera recordings)2,3
G08-1465 38 GIRQP/GMRQP AN No signs of TSE (difficult to milk)* Inconclusive (difficult to milk (kicking)1,4
G08-1430 106 GIRQP/GIRQP AN Scrapie (positive scratch test) Scrapie (see Fig. 1)2,3
Scrapie positive (CNS and LRS)
G08-1451 98 GIRQP/GMRQP AN No signs of TSE Inconclusive (pruritic behaviour and abnormal rising on camera recordings)2-4
G08-1415 98 GIRQS/GMRQP TG No signs of TSE Inconclusive (prefers to stay close to pen, kicking when hind limbs touched, head tremor at times, hair loss on left flank not previously seen, pruritic activity on camera recordings)2-4
G08-1383 99 GIRQS/GMRQP SA No signs of TSE Inconclusive (inconclusive scratch test)2-4
G08-1365 107 GIRQP/GMRQP SA No signs of TSE Inconclusive (inconclusive scratch test)2,3
G08-1475 86 GIRQP/GIRQP AN No signs of TSE (difficult to milk)* Scrapie (see Fig. 1), difficult to milk (kicking)2-4
G08-1373 107 SIRQP/GIRQP SA Inconclusive (head and body tremor) Scrapie (see Fig. 1)2,3
G08-1447 57 GIRQP/GIRQP AN Inconclusive (head tremor, nervous on head tests) Scrapie (see Fig. 1), difficult to milk (kicking, sitting down), pruritic activity on camera recordings2-4
G08-1340 39 GIRQP/GMRQP AN Scrapie (positive scratch test, teeth grinding) No signs of TSE (negative scratch test)1
G08-1460 98 GIRQP/GIRQP AN Scrapie (positive scratch test, repeated startle to auditory stimuli) Scrapie (see Fig. 1)2-4
  1. AN = Anglo-Nubian, SA = Saanen, TG = Toggenburg.
  2. The clinical TSE status on arrival was assessed using the short protocol; for the assessment of the clinical TSE status prior to cull clinical assessments (short1 or long2 protocol), camera recordings3 and behaviour at milking4 were taken into consideration.
  3. * Inconclusive signs if behaviour during milking was included.