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Table 3 Signs of scrapie-negative goats kept for milk collection or monitoring of clinical progression

From: Monitoring of clinical signs in goats with transmissible spongiform encephalopathies

Animal Days at VLA Genotype
127-142-211-222-240
Breed Clinical status & signs at arrival Clinical status & signs prior to cull
G08-1136 38 GIRQP/GMRQP AN No TSE signs (difficult to milk)* No TSE signs1,4
G08-1376 38 GIRQP/GIRQP AN No TSE signs (difficult to milk)* No TSE signs1,4
G08-1382 39 GIRQP/GMRQP AN No TSE signs (difficult to milk)* No TSE signs1,4
G08-1122 65 GIRQP/GMRQP AN No TSE signs (difficult to milk)* No TSE signs2-4
G08-1342 25 GIRQP/GIRQP AN No TSE signs (difficult to milk)* Inconclusive (kicking and lying down at milking)2-4
G08-1454 37 GIRQP/GMRQP SA No TSE signs (difficult to milk)* Inconclusive (leg tremor)1,4
G08-1115 65 GMRQP/GMRQP AN Inconclusive (head and body tremor, teeth grinding) Inconclusive [body tremor, inconclusive scratch test (crouching), also diarrhoea]2-4
G08-1144 39 GMRQP/GMRQP SA Scrapie (positive scratch test, repeated startle to auditory stimuli) Inconclusive (pruritic behaviour on camera recordings but negative scratch test)1,3
  1. AN = Anglo-Nubian, SA = Saanen.
  2. The clinical TSE status on arrival was assessed using the short protocol; for the assessment of the clinical TSE status prior to cull clinical assessments (short1 or long2 protocol), CCTV observations3 and behaviour at milking4 were taken into consideration.
  3. * Inconclusive signs if behaviour during milking was included.