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Table 1 Incubation periods

From: Accumulation and dissemination of prion protein in experimental sheep scrapie in the natural host

Group

Challenge

Age at challenge (days)

Attack rate

Mean incubation period (days)

Range, (SD)

1

1 g RBP1 oral

14

25/25

192

185–204, (6.9)

2

5 g RBP1 oral

14

28/28

185

178–198, (7.4)

3

1 g RBP1 oral (after 3 g scrapie negative sheep brain)

245

8/8

345

198–639, (186)

4

Exposure to groups 1 and 2

42 days onwards

4/4

649*

592–716, (61)

5

3 g Scrapie negative sheep brain

14 days

8/8

1085**

880–1231 (156)

  1. * Days since mixing with groups 1 and 2
  2. ** Age at death, as exact timing of infection unknown