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Table 1 Data for experimental exposure groups and VLA scrapie flock cohorts.

From: The evaluation of exposure risks for natural transmission of scrapie within an infected flock

Exposure Group

Birth cohort

Dam status

Area(s) exposed to

Length of time exposed to infected environment

Type of contact with VLA scrapie flock sheep

Number in group at start of exposure

Number of clinical cases

Median

survival time (days)

Range survival time (days)

1

2003

N

None

N/A

None

7

0

-

-

2

2003

N

All

12 months

Direct

4

3*

792

747-792

3

2003

N

Lambing pens

6 weeks

Direct

6

4*

730

663-742

4

2003

N

Lambing pens

6 weeks

Indirect

6

5*

770

709-836

5

2002

A

All

6 weeks

Direct

5

5

659

639-857

6

2002

A

All

3 months

Direct

5

5

780

644-857

7

2002

A

All

12 months

Direct

5

5

728

716-775

8

2003

N

Pasture

6 weeks

Indirect

5

2

-

1094-1673

9

2003

N

Pasture

3 months

Indirect

5

4

1299

836-1299

10

2002

N

Pasture

12 months

Indirect

8

6*

794

729-869

11

2003

N

Pasture

6 weeks

Direct

5

5

817

728-1008

12

2003

N

Pasture

3 months

Direct

5

4*

776

684-791

13

2003

N

Pasture

12 months

Direct

5

5

807

742-823

VLA scrapie flock

2002

A

All

Birth to clinical endpoint

Direct

8

7*

709

592-730

VLA scrapie flock

2003

A

All

Birth to clinical endpoint

Direct

46

41*

748

601-1184

  1. Dam status - N, naïve, TSE-free; A, scrapie affected.
  2. * 'Number of clinical cases' is different to 'Number in group at start of exposure' due to intercurrent deaths.