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Table 3 Range and median of hematology, serum chemistry and urine parameters in Bernese Mountain dogs and control dogs at the first examination and after a median of 2.7 years.

From: Follow-up of Bernese Mountain dogs and other dogs with serologically diagnosed Borrelia burgdorferiinfection: What happens to seropositive animals?

    Bernese Mountain dogs (N = 53) Control dogs (N = 30)
    Result of B. burgdorferi serology at the first examination
Parameters Reference range   positive (N = 22) negative (N = 31) positive (N = 11) negative (N = 19)
Hematocrit [%] 42–55 1st ex. 41–63 (51) 41–60 (50) 40–57 (51) 43–54 (48)
   2nd ex. 36–54 (46) 36–54 (46) 34–49 (44) 41–55 (47)
    [P < 0.001]* [P < 0.001]* [P = 0.004]* [P = 0.06]
Urea [mmol/L] 3.8–9.4 1st ex. 3.1–8.9 (6.7) 4.0–13.1 (6.5) 3.8–7.7 (5.6) 3.4–8.6 (5.6)
   2nd ex. 3.9–13.7 (6.5) 3.6–15.1 (6.9) 2.8–6.4 (4.8) 1.7–6.7 (4.2)
    [P = 0.73] [P = 0.34] [P = 0.21] [P = 0.001]*
Creatinine [μmol/L] 64–125 1st ex. 80–120 (102) 74–155 (100) 72–119 (87) 66–114 (82)
   2nd ex. 64–138 (108) 65–260 (99) 59–110 (78) 52–107 (72)
    [P = 0.85] [P = 0.96] [P = 0.003]* [P < 0.001]*
Protein [g/L] 56–71 1st ex. 58–74 (64) 43–74 (63) 53–65 (61) 50–67 (61)
   2nd ex. 53–70 (64) 55–73 (64) 59–69 (61) 58–74 (63)
    [P = 0.77] [P = 0.002]* [P = 0.28] [P = 0.02]
Albumin [g/L] 29–37 1st ex. 25–33 (30) 21–34 (30) 28–35 (32) 28–35 (31)
   2nd ex. 22–36 (33) 28–38 (35) 30–40 (33) 30–40 (35)
    [P = 0.001]* [P < 0.001]* [P = 0.03] [P < 0.001]*
Urine specific gravity   1st ex. 1.010–1.049 (1.030) 1.006–1.050 (1.028) 1.011–1.048 (1.021) 1.007–1.048 (1.027)
   2nd ex. 1.006–1.050 (1.030) 1.007–1.050 (1.034) 1.012–1.046 (1.023) 1.006–1.042 (1.026)
    [P = 0.21] [P = 0.27] [P = 0.81] [P = 0.41]
Urine protein-to-creatinine ratio (UPC)   1st ex. 0.06–0.28 (0.11) 0.06–0.42 (0.11) 0.07–0.48 (0.12) 0.08–0.21 (0.11)
   2nd ex. 0.05–0.36 (0.14) 0.06–0.44 (0.10) 0.06–0.92 (0.09) 0.06–0.53 (0.11)
    [P = 0.05] [P = 0.79] [P = 0.13] [P = 0.91]
Urine protein on dip stick   1st ex. 15 neg., 3 pos. 21 neg., 5 pos. 9 neg., 2 pos. 11 neg., 6 pos
   2nd ex. 6 neg., 11 pos. 7 neg., 18 pos. 4 neg., 7 pos. 9 neg., 8 pos.
    [P = 0.001]* [P < 0.001]* [P = 0.03] [P = 0.27]
Micro-albuminuria test   1st ex. 11 neg., 8 pos. 22 neg., 4 pos. 10 neg. 14 neg., 3 pos.
   2nd ex. 11 neg., 6 pos. 20 neg., 5 pos. 10 neg., 1 pos. 13 neg., 4 pos.
    [P = 0.69] [P = 0.25] [P = 1.00] [P = 1.00]
  1. *Significant difference between first and second examination at P < 0.006 due to Bonferroni correction.
  2. ex. = examination