Skip to main content

Table 4 Significantly down-regulated genes in mammary tissue challenged with S. aureus.

From: Identification of immune genes and proteins involved in the response of bovine mammary tissue to Staphylococcus aureus infection

Function Gene symbol Genbank accession Genbank description
Chemokine, cytokine and intercellular signalling    
  IL1A M37210 Bovine interleukin 1-alpha (IL-1-alpha) mRNA, complete cds.
  NGFB NM_002506 Homo sapiens nerve growth factor, beta polypeptide (NGFB), mRNA
  IL13 AF072807 Bos taurus interleukin-13 precursor (IL-13) mRNA, partial cds
  RETN NM_183362 Bos taurus resistin (RETN), mRNA
  SFRP1 NM_003012 Homo sapiens secreted frizzled-related protein 1 (SFRP1), mRNA
  SPP1 AF492837 Homo sapiens secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) (SPP1), mRNA
Cytoskeleton and extracellular matrix    
  CD24 NM_013230 Homo sapiens CD24 antigen (small cell lung carcinoma cluster 4 antigen) (CD24),
  EPB41L1 NM_174528 Homo sapiens erythrocyte membrane protein band 4.1-like 1 (EPB41L1), transcript
  FLNA NM_001456 Homo sapiens filamin A, alpha (actin binding protein 280) (FLNA), mRNA
  ITGA3 NM_002204 Homo sapiens integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor
  ITGB4 NM_000213 Homo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  KRT5 BC006780 Homo sapiens keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber
  PFN2 NM_053024 Homo sapiens profilin 2 (PFN2), transcript variant 1, mRNA
  VCAM1 NM_174484 Homo sapiens vascular cell adhesion molecule 1 (VCAM1), transcript variant 2, mRNA
  VCL NM_014000 Homo sapiens vinculin (VCL), transcript variant meta-VCL, mRNA
  VIM NM_003380 Homo sapiens vimentin (VIM), mRNA
Cell surface receptors    
  CX3CR1 NM_001337 Homo sapiens chemokine (C-X3-C motif) receptor 1 (CX3CR1), mRNA
  ERBB4 NM_005235 Homo sapiens v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
  FGFR1 NM_023106 Homo sapiens fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2)
  KIT NM_000222 Homo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT)
  MET V00654 Homo sapiens met proto-oncogene (hepatocyte growth factor receptor) (MET), mRNA
  PDGFRA NM_006206 Homo sapiens platelet-derived growth factor receptor, alpha polypeptide (PDGFRA)
  TGFBR3 NM_003243 Homo sapiens transforming growth factor, beta receptor III (betaglycan, 300 kDa)
Intracellular signaling    
  PP M95283 Homo sapiens pyrophosphatase (inorganic) (PP), mRNA
  PPM1J NM_005167 Homo sapiens protein phosphatase 1J (PP2C domain containing) (PPM1J), mRNA
  PRKCA NM_174435 Homo sapiens protein kinase C, alpha (PRKCA), mRNA
  RHOB NM_004040 Homo sapiens ras homolog gene family, member B (RHOB), mRNA
Apoptosis    
  CIDEA NM_001279 Homo sapiens cell death-inducing DFFA-like effector a (CIDEA), transcript variant
  CLU NM_173902 Bos taurus clusterin (CLU), mRNA.
  EPHA1 NM_005232 Homo sapiens EphA1 (EPHA1), mRNA
  EPHA7 NM_004440 Homo sapiens EphA7 (EPHA7), mRNA
Transcription factor or regulator    
  DDX5 NM_004396 Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 (DDX5), mRNA
  NFATC4 NM_004554 Homo sapiens nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent
  TEBP NM_006601 Homo sapiens inactive progesterone receptor, 23 kD (TEBP), mRNA
Assorted    
  CAMP NM_174825 Homo sapiens cathelicidin antimicrobial peptide (CAMP), mRNA
  CSN1S1 NM_181029 Homo sapiens casein alpha s1 (CSN1S1), mRNA
  FLJ20920 NM_025149 Homo sapiens hypothetical protein FLJ20920 (FLJ20920), mRNA
  GATM NM_001482 Homo sapiens glycine amidinotransferase (L-arginine:glycine amidinotransferase
  GPX4 NM_002085 Homo sapiens glutathione peroxidase 4 (phospholipid hydroperoxidase) (GPX4)
  LOC529035 AF109167 Bos taurus immunoglobulin IgA heavy chain constant region gene, partial cds
  18S rRNA AY150548 Cervus nippon 18S ribosomal RNA gene, partial sequence
  SNX19 AC150499 Homo sapiens similar to Sorting nexin 19 (LOC399979), mRNA