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Table 5 Survival analysis test to compare the times of the first appearance of a particular clinical sign in BSE positive and negative cases.

From: Pruritus is a common feature in sheep infected with the BSE agent

  Presence during the monitoring period P-value *
Clinical sign Negative cases (n) Positive cases (n) Log-rank test Wilcoxon test
Behaviour change 17 16 ++  
Rubbing/scratching 34 23 ns  
Nibbling 25 21 +  
Positive scratch test 4 18 +++  
Fleece change 28 18   ns
Alopecia 4 14 +++  
Skin lesions 5 10 +  
Self-induced scratch response 7 18 +++  
Bruxism when handled 9 9 +++  
Bruxism when free during examination 7 5   ns
Bruxism at observation 17 17 +  
Tremors 2 14 +++  
Ataxia 2 13   +++
Weight loss 29 22   +
Loss of body condition 20 18 +++  
  1. * P-values: + ≤ 0.04;
  2. ++ ≤ 0.001;
  3. +++ ≤ 0.0001;
  4. ns statistically not significant (P > 0.05)