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Table 4 Clinical findings in non-pruritic BSE cases of the oral BSE pathogenesis study

From: Pruritus is a common feature in sheep infected with the BSE agent

Animal

SM1391

SM1430

SM1394

SP3652

SM1435

SM1404

Breed and genotype

Romney ARQ/ARQ

Romney ARQ/ARQ

Romney ARQ/ARQ

Suffolk ARQ/ARQ

Romney ARQ/ARQ

Romney ARQ/ARQ

MPI

16

16

22

16

22

22

Postmortem test result

HP neg. IHC pos.

HP neg. IHC pos.

HP neg. IHC pos.

HP neg. IHC pos.

HP pos. IHC pos.

HP pos. IHC pos.

Behaviour change

No

No

No

No

N/A

No

Pruritic behaviour 1

No

No

Rubbing once

No

Rubbing once

No

Fleece change

No

No

No

No

No

No

Skin Lesion

No

No

No

No

No

No

Bruxism when observed or examined

No

No

No

No

No

No

Tremors

No

No

No

No

N/A

No

Ataxia

No

No

No

No

No

No

Weight loss

No

<5%

No

No

<5%

<5%

  1. 1 The display of a positive scratch test, a self-induced scratch response, self-nibbling, rubbing or scratching
  2. HP = Histopathological examination of the brain
  3. IHC = Immunohistochemical examination of the brain
  4. neg./pos. = negative/positive
  5. N/A = not assessed
  6. Romney sheep were inoculated at approximately six months of age, Suffolk sheep at approximately four months of age.