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Table 4 Mixed-inheritance model parametersa for dichotomous deafness in Jack Russell Terriers

From: Heritability and complex segregation analysis of deafness in Jack Russell Terriers

  Polygenic Variance Major Locus Variance Additive Effect (a) Dominance Deviation (d) τAAb τAB τBB Frequency (q)
General Major Locus, Mendelian Transmission
Mean 1.48 8.46 3.64 -2.65 1.0 0.5 0.0 0.84
Median 1.53 9.72 3.89 -2.57 - - - 0.83
SD 0.84 10.21 1.18 1.35 - - - 0.11
Eff Sample Sizec 1417.3 1007.3 980.2 1013.6 - - - 1198.6
Conv Score (p)d 1.32 (0.19) 1.55 (0.12) 1.68 (0.09) 1.71 (0.09) - - - 1.49 (0.14)
HDRe 95% Low 0.00 0.00 1.48 -5.21 - - - 0.38
HDR 95% High 3.22 33.14 7.77 0.06 - - - 1.00
Recessive Major Model, Mendelian Transmission
Mean 2.21 13.19 3.68 -3.68 1.0 0.5 0.0 0.74
Median 2.33 12.32 3.65 -3.65 - - - 0.75
SD 0.60 6.03 0.84 0.84 - - - 0.41
Eff Sample Size 1330.9 1121.0 1032.6 1032.6 - - - 1064.1
Conv Score (p) -1.27 (0.20) 1.51 (0.13) 1.74 (0.08) 1.74 (0.08) - - - 1.42 (0.16)
HDR 95% Low 0.39 0.00 2.15 -6.23 - - - 0.44
HDR 95% High 3.16 45.89 7.42 -1.03 - - - 1.00
General Major Locus, Non-Mendelian Transmission
Mean 1.46 6.53 4.13 -3.01 0.63 0.52 0.18 0.94
Median 1.57 6.34 4.36 -3.29 0.70 0.51 0.01 0.99
SD 0.88 8.18 1.62 1.57 0.05 0.05 0.13 0.03
Eff Sample Size 1387.6 1109.2 1290.3 1088.1 1172 1043 941 1186.4
Conv Score (p) 1.18 (0.24) 1.40 (0.16) 1.37 (0.17) 1.19 (0.23) 1.08 (.28) 1.19 (.23) 1.75 (.08) 0.97 (0.33)
HDR 95% Low 0.00 0.00 0.53 -7.11 0.52 0.26 0.00 0.75
HDR 95% High 3.23 33.69 8.04 -0.48 0.86 0.66 0.63 1.00
  1. a Estimates are taken from a Gibbs sample of 9,000 values.
  2. b Mendelian transmission parameter; the probability of transmitting an "A" allele. For Mendelian transmission these values are fixed as 1.0, .50 and 0.0 for putative major genotypes AA, AB and BB, respectively. Non-Mendelian transmission implies estimation of these values from the data.
  3. c Effective sample size.
  4. d Gibbs sample convergence statistic; Geweke (1992).
  5. e Highest density region