Table 1 Assignment, genomic location and the degree of sequence conservation compared to human of the canine DCM candidate genes.
Gene | Annotation of canine gene | CFA | Similarity to human 4 | |||
|---|---|---|---|---|---|---|
Identification sequence 1 | ENST 00000..2 | AAEX010... 3 | Dog prot. (a.a.) | |||
ACTC | AF203019 (C), | 290378 | 13478 | 377 | 30 | 100% AAB59619 |
AF203020 (C) | ||||||
CAV1 | U47060 (C) | 341049 | 48546, 48547 | 178 | 14 | 96% NP_001744 |
CSRP3 | BC024010 (H) | 265968 | 17412 | 194 | 21 | 99% AAH24010 |
DES | BK005142 (C) | 273074 | 55032 | 469 | 37 | 97% NP_001918 |
LDB3 | NM_007078 (H) | 361816 | 16582, 16583(5), 16584 | 660 | 4 | 79% AB014513 |
LMNA | AF427092 (C) | 310777 | 12733, 12734 | 665 | 7 | 98% CAI15522 |
MYH7 | NM_000257 (H) | 355349 | 41099, 41100 | 1935 | 8 | 98% NP_000248 |
PLN | Y00399 (C) | 357525 | 14037 | 52 | 1 | 96% CAI21610 |
SGCD | NM_000337 (H) | 303006 | 16848, 16849(5), 16850(5), 16851, 16852 | 289 | 4 | 98% NP_000328 |
TCAP | NM_003673 (H) | 309889 | 22011 | 167 | 9 | 90% CAA09479 |
TNNI3 | AF506750 (C) | 344887 | 53923 | 211 | 1 | 95% CAG46782 |
TNNT2 (ex 2–14) | NM_000364 (H) | 367317 | 13359, 13360 | 254 | 7 | 90% NP_000355 |
TPM1 | NM_000366 (H) | 288398 | 08742 | 284 | 30 | 99% AAH07433 |
VCL | NM_003373 (H) | 211998 | 16404 | 1134 | 4 | 99% NP_054706 |