Table 2 Ki67 labelling index in canine MCTs: correlations with multiple pathologic variables
Pathologic variables | Ki67 labelling index | (p value) | |||
|---|---|---|---|---|---|
median | min. | max. | IR | ||
Histological grade | |||||
I | 7.1 | 3.3 | 14.9 | 3.2 | |
II | 13.3 | 3,9 | 32.7 | 12.9 | p < 0,001 |
III | 32.2 | 15.4 | 46.6 | 8.5 | |
Necrosis | |||||
No | 9.7 | 3.3 | 38.6 | 10.2 | p < 0,001 |
Yes | 27.7 | 6.2 | 46.6 | 20.6 | |
Growth pattern | |||||
well circumscribed | 8.2 | 4.1 | 46.6 | 13.8 | P = 0,158 |
Invasive | 12.7 | 3.3 | 45.1 | 17.4 | NS |
Ulceration | |||||
No | 9.8 | 3.3 | 46.6 | 10.8 | p < 0,001 |
Yes | 29.4 | 4.5 | 45.1 | 19.4 | |
Mitoses (per high power field) | |||||
0 | 8.6 | 3.3 | 29.7 | 4.7 | |
1 | 16.0 | 9.3 | 30.8 | 11.3 | p < 0,001 |
2 | 29.2 | 15.4 | 45.1 | 15.1 | |
≥ 3 | 33.7 | 30.9 | 46.6 | 7.5 | |
CD117 staining pattern | |||||
membrane-associated | 9.2 | 3.3 | 29.7 | 6.0 | |
cytoplasmic focal | 23.9 | 4.1 | 46.6 | 21.7 | p < 0,001 |
cytoplasmic diffuse | 19.1 | 5.8 | 45.1 | 21.6 | |