Table 1 CD117 immunoexpression in canine MCTs (membrane-associated versus cytoplasmic staining): correlations with multiple pathologic variables
Pathologic variables | CD117 expression pattern | P value | |
|---|---|---|---|
membrane-associated | cytoplasmic | ||
Histological grade | |||
I | 24 (49.0%) | 11 (20.4%) | p < 0,001 |
II | 22 (44.0%) | 23 (42.6%) | |
III | 3 (6.1%) | 20 (37.0%) | |
Necrosis | |||
No | 44 (89.8%) | 29 (53.7%) | p < 0,001 |
Yes | 5 (10.2%) | 25 (46.3%) | |
Growth pattern | |||
well circumscribed | 7 (14.3%) | 5 (9.3%) | P = 0,427 |
invasive | 42 (85.7%) | 49 (90.7%) | (NS) |
Ulceration | |||
No | 40 (81.6%) | 34 (63.0%) | P = 0,035 |
yes | 9 (18.4%) | 20 (37.0%) | |
Mitosis (per high power field) | |||
0 | 37 (75.5%) | 22 (40.7%) | |
1 | 11 (22.4%) | 8 (14.8%) | p < 0,001 |
2 | 1 (2.0%) | 10 (18.5%) | |
≥ 3 | 0 (0.0%) | 14 (25.9%) | |