Table 1 Cytokine transcript levels in terminal ileum from sheep with paratuberculosis infected sheep and controls
Gene | Multibacillary | Paucibacillary | Asymptomatic | Control |
|---|---|---|---|---|
IL-1α | 691 ± 56 | 38 ± 14 | 51 ± 42 | 20 ± 8 |
IL-1β | 30839 ± 41353 | 16470 ± 8559 | 4176 ± 2557 | 8613 ± 6090 |
IL-3 | 29 ± 74 | 1 ± 3 | 87 ± 131 | 0 ± 0 |
IL-6 | 71778 ± 124310 | 11023 ± 2980 | 4996 ± 1698 | 5473 ± 7583 |
IL-8 | 1448098 ± 1453346 | 609805 ± 511880 | 480573 ± 601312 | 150388 ± 59472 |
IL-10 | 305964 ± 127868 | 174186 ± 82536 | 126941 ± 94659 | 240619 ± 185599 |
IL-12 | 7178 ± 7381 | 7589 ± 6467 | 4506 ± 5179 | 1615 ± 2436 |
IL-18 | 102838 ± 45161 | 84037 ± 34888 | 42352 ± 10066 | 126047 ± 41771 |
GM-CSF | 2512 ± 1067 | 2973 ± 963 | 1786 ± 684 | 1986 ± 552 |
IFNγ | 3354 ± 1063 | 5209 ± 2554 | 2529 ± 1620 | 1537 ± 427 |
TGF-β | 50349 ± 30161 | 28007 ± 13809 | 21871 ± 11222 | 14519 ± 6032 |
TNFα | 21113 ± 13334 | 11681 ± 7914 | 7492 ± 4925 | 2770 ± 2120 |
TRAF-1 | 11504 ± 6076 | 20087 ± 10563 | 5018 ± 5134 | 3708 ± 1662 |