| Astrocytes (GFAP) | Microglia (F4/80) |
---|
Treatment
| 6 hours | 24 hours | 6 hours | 24 hours |
Saline | 4/16 (25%) | 2/14 (14,3%) | 1/16 (6,2%) | 2/14 (14,3%) |
IL-12/IL-18 | 2/16 (12,5%) | 5/15 (33,3%) | 7/15 (46,7%) | 8/14 (57,1%) |
- Mice were sacrificed 6 or 24 hours after intracerebral inoculation. Observation was made in different areas of brain, by different independent observers. Numbers are referred to the fields where it was observed an increase of reactivity upon the examined fields.