Figure 4From: A proteomics study of the response of North Ronaldsay sheep to copper challengeDifferential expression of NADP+-dependent isocitrate dehydrogenase in Cambridge and North Ronaldsay sheep at both moderate and high copper challenge. The region of the 2-D gel encompassing a protein identified as cytosolic NADP+-dependent isocitrate dehydrogenase by MALDI-ToF MS and peptide mass fingerprinting is shown for two control animals, and two copper-challenged animals at both moderate and high copper loading. The copper level in each individual liver (mean value of dorsal and ventral lobes), determined by ICP-MS is indicated.Back to article page