Figure 3
Different PrPSc immunolabelling in the pre-1975 and post-1990 group. A) Olivary nucleus, pre-1975 pool. Immunolabelling is predominantly intraneuronal – Group 1 type. B) Olivary nucleus, post-1990 pool. Immunolabelling is predominantly in the neuropil – Group 2 type. C) Caudate nucleus, pre-1975 pool. Immunolabelling is predominantly intracellular (intraneuronal and intraglial) – Group 1 type. D) Caudate nucleus, post-1990 pool. Immunolabelling is predominantly in the neuropil, with prominent stellate forms – Group 3 type.