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Table 1 Measurement of scrapie infectivity in fish tissues by mouse bioassay. Brains from recipient mice inoculated with turbot or trout tissues from either oral or multiple parenteral routes were assayed for PrPSc by Western blot. Whenever samples were available, histology and/or immunohistochemistry was performed. Asterisks indicate mice contributing to the lesion profiles curve of the fish-passaged 139A (Figure 3)

From: Scrapie infectivity is quickly cleared in tissues of orally-infected farmed fish

A. Tissues from infected fish via the oral route
  Turbot Trout
Days after infection Muscle Intestine Brain Spleen Muscle Intestine Brain Spleen
1 0/10 0/8 0/8 - 0/10 1/8 0/5 -
15 0/7 0/8 0/6 - 0/10 0/8 0/13 -
30 0/10 0/8 0/10 - 0/8 0/8 0/9 -
60 0/9 0/6 0/8 - 0/7 0/6 0/6 -
90 0/7 0/8 0/9 - 0/10 0/11 0/10 -
B. Tissues from infected fish via multiple parenteral routes
15 - - 2/8 4/7 * - - 0/9 1/9 *
90 - - 1/7 * 0/8 - - 0/11 0/11