Skip to main content

Table 1 The effect of selected antiviral drugs on number and size of feline herpesvirus 1-induced plaques in Crandell-Rees feline kidney cells

From: In vitrocomparison of antiviral drugs against feline herpesvirus 1

Antiviral drug

IC50 (NUMBER)

IC50 (SIZE)

Acyclovir

56 μg/ml (248.7 μM)

15 μg/ml (66.6 μM)

Ganciclovir

3.2 μg/ml (12.5 μM)

0.4 μg/ml (1.7 μM)

Cidofovir

6 μg/ml (21.5 μM)

0.2 μg/ml (0.7 μM)

Foscarnet

27 μg/ml (140.6 μM)

7 μg/ml (36.4 μM)

Adefovir

20 μg/ml (73.2 μM)

4 μg/ml (14.6 μM)

PMEDAP

4.8 μg/ml (14.3 μM)

0.9 μg/ml (2.7 μM)

  1. IC50 (NUMBER): concentration of a product required to reduce the plaque number with 50 % in comparison with untreated cells
  2. IC50 (SIZE): concentration of a product required to reduce the plaque size with 50% in comparison with untreated cells
  3. PMEDAP: 9-[2-phosphonylmethoxyethyl]-2, 6-diaminopurine