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Table 1 Peruvian Paso horses affected with DSLD

From: Degenerative suspensory ligament desmitis as a systemic disorder characterized by proteoglycan accumulation

 

age, sex

onset of symptoms

clinical

family affected

legs

patella

heart

PA

aorta

eyes

other tissues

ultrasound

1

1 y, M

6 mos

four

sire

4 mod

ND

cor +

ND

+

both+

nuchal+

2/2 front SLs

2

1 y, F

6 mos

four

sire

4 mild

ND

cor +

ND

+

-

nuchal, lung +

2/2 front SLs

3

18 mo M

6 mos

four

parents

4 mild

ND

ND

ND

ND

ND

nuchal+

ND

4

18 mo M

6 mos

four

parents

4 mod

ND

ND

ND

ND

ND

nuchal+

ND

5

1.5 y, M

at 1 y

four

dam

4 mild

+

-

+

-

both+

lung +

4 SLs

6

2 y, F

birth

four

sire

4 mod

ND

ND

ND

+

ND

ND

¾ SLs

7

3 y, F

6 mos

rear

parents

4 mild

+

cor +

ND

+

both +

nuchal, lung +

4 SLs

8

3 y, M

1 year

front legs

no

4 severe

ND

cor +

ND

+

ND

nuchal+

ND

9

7 y, F

years

four

dam

4 severe

ND

valve+

+

+

ND

lung +

2/4 SLs

10

8 y, M

years

four

sire, foals

1 SL exam, mod*

ND

ND

ND

ND

L eye +

nuchal+

4 SLs

11

9 y, F

at 9 y

rear

dam

4 severe

ND

valve+

+

+

ND

lung +

4 SLs

12

9 y, M

at 6 y

four

no

4 mild

+

cor +

+

+

both+

-

4 SLs

13

9 y, M

years

fallen crest, legs

dam

4 mild

ND

cor +

ND

-

both +

nuchal, lung +

ND

14

11 y, F

years

four

no

1 SL exam, mild*

ND

ND

ND

ND

R eye +

nuchal+

2/2 hind SLs

15

15 y, F

years

four

no

4 mod

ND

ND

ND

+

ND

ND

4 SLs

16

15 y, F

years

front

foal

4 mod

+

cor +

PA+

+

both +

nuchal+

ND

17

15 y, F

years

four

sire, son

4 mod

ND

cor +

ND

+

both +

nuchal, shoulder+

ND

18

18 y, F

years

four

no

1 leg exam, severe*

ND

ND

ND

ND

ND

ND

4 SLs

19

18 y, F

years

rear legs

foals

4 mild

ND

ND

ND

-

R eye +

nuchal, lung +

4 SLs

20

21 y, M

late onset

four

no

4 mod

+

cor +

-

-

R eye +

-

4 SLs

21

21 y, M

years

legs

no

4 severe

ND

cor +

ND

+

R eye +

lung +

4 SLs

22

unknown

unknown

unknown

no

4 mild

ND

-

ND

-

ND

-

ND

  1. Age: age at necropsy; ND: not done; legs: SDFT, DDFT and SL; cor: coronary artery; PA: pulmonary artery; nuchal: nuchal ligament
  2. Mild, mod (moderate), severe: describes the average severity of pathology in examined leg tendons and ligaments; +: accumulation of proteoglycans in other tissues; -: no proteoglycan accumulation
  3. *only limited tissue was available for examination