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Table 3 Mean values (± standard deviation) of biochemical variables in donkeys ( n= 10) injected with digoxin

From: Influence of the cardiac glycoside digoxin on cardiac troponin I, acid–base and electrolyte balance, and haematobiochemical profiles in healthy donkeys (Equus asinus)

Time

Glucose (mmol/L)

CA (mmol/L)

BUN (mmol/L)

CRE (μmol/L)

AST (U/L)

CK (U/L)

GGT (U/L)

TBIL (μmol/L)

TP (g/L)

ALB (g/L)

GLOB (g/L)

T0

3.8 ± 0.6

3.0 ± 0.1

6.1 ± 0.6

44 ± 8

618 ± 157

1339 ± 1275

56 ± 10

2.2 ± 0.3

73.5 ± 7.2

35.9 ± 4.4

37.6 ± 11.1

T1

4.6 ± 0.9b

2.9 ± 0.1

6.1 ± 0.4

44 ± 9

632 ± 137

1356 ± 1280

58 ± 14

2.5 ± 0.4

75.0 ± 5.6

45.4 ± 14.2

36.2 ± 11.2

T2

5.1 ± 0.8b

3.0 ± 0.1

6.2 ± 0.4

42 ± 12

627 ± 136

1326 ± 1204

55 ± 8

2.5 ± 0.4

74.4 ± 4.3

37.9 ± 5.8

36.6 ± 9.7

T3

5.2 ± 0.8b

3.0 ± 0.2

6.2 ± 0.5

44 ± 13

644 ± 114

1219 ± 1117

49 ± 12

2.8 ± 0.8

74.0 ± 3.7

37.8 ± 5.9

36.1 ± 9.0

T4

6.2 ± 1.1b

2.9 ± 0.3

6.2 ± 0.4

43 ± 13

791 ± 226

1232 ± 1102

52 ± 11

2.5 ± 0.4

74.6 ± 4.6

36.9 ± 4.2

38.1 ± 8.0

T5

5.3 ± 0.9b

3.1 ± 0.2

6.0 ± 0.7

37 ± 3

778 ± 243

2335 ± 2402

50 ± 9

2.2 ± 0.3

77.2 ± 5.1

39.6 ± 4.6

38.1 ± 9.0

T6

5.8 ± 1.2b

3.0 ± 0.1

6.1 ± 0.4

39 ± 9

743 ± 240

1560 ± 980

51 ± 8

2.5 ± 0.4

75.2 ± 6.4

37.5 ± 5.7

37.3 ± 11.3

T7

4.9 ± 0.5b

3.0 ± 0.1

6.4 ± 0.5

44 ± 8

576 ± 186

1072 ± 713

60 ± 13

2.5 ± 0.7

74.6 ± 7.0

39.5 ± 5.8

34.9 ± 12.1

  1. CA, calcium; BUN, blood urea nitrogen; CRE, creatinine; AST, aspartate aminotransferase; GGT, γ-glutamyl transferase; CK, creatine kinase; TBIL, total bilirubin, TP, total protein; ALB, albumin; GLOB, globulin. T0, immediately prior to injection of digoxin; T1-T7, 1, 2, 3, 4, 24, 48 and 72 h after digoxin administration. bDiffer significantly at P < 0.05 compared to pre-injection values.