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Table 1 Mean values (± standard deviation) of acid–base and electrolyte parameters in donkeys ( n= 10) injected with digoxin

From: Influence of the cardiac glycoside digoxin on cardiac troponin I, acid–base and electrolyte balance, and haematobiochemical profiles in healthy donkeys (Equus asinus)

Time pH PCO2(mmHg) PO2(mmHg) BE (mmol/L) HCO3¯ (mmol/L) SO2(%) Sodium (mmol/L) Potassium (mmol/L) Chloride (mmol/L) AG (mmol/L) Lactate (mmol/L)
T0 7.42 ± 0.02 42.0 ± 2.6 31.2 ± 1.9 2.6 ± 1.0 27.1 ± 0.9 60.5 ± 3.4 132 ± 3 4.5 ± 0.3 104 ± 2.9 9.3 ± 0.4 1.9 ± 0.5
T1 7.43 ± 0.03 41.7 ± 3.3 30.7 ± 2.0 3.2 ± 1.5 27.6 ± 1.2 56.0 ± 7.3 133 ± 4 4.6 ± 0.5 105 ± 3.8 10.3 ± 1.6 1.0 ± 0.2b
T2 7.45 ± 0.04 39.4 ± 2.8b 30.0 ± 0.8 2.9 ± 1.9 27.1 ± 1.4 60.5 ± 1.2 132 ± 5 4.4 ± 0.5 105 ± 3.4 8.6 ± 0.9 1.2 ± 0.4b
T3 7.45 ± 0.01b 38.3 ± 0.8b 33.6 ± 2.1b 2.9 ± 2.4 26.8 ± 1.7 68.5 ± 3.2b 132 ± 3 4.8 ± 0.6 105 ± 3.7 8.8 ± 1.1 1.4 ± 0.6b
T4 7.44 ± 0.02 37.0 ± 2.2b 33.8 ± 1.2b 2.0 ± 1.5 26.2 ± 1.4 65.7 ± 4.6b 131 ± 3 4.2 ± 0.5 106 ± 3.5 9.5 ± 2.2 1.2 ± 0.3b
T5 7.42 ± 0.01 39.7 ± 2.3b 45.7 ± 16.6b 2.4 ± 1.3 26.6 ± 1.4 74.4 ± 10.9b 133 ± 4 5.0 ± 1.0 103 ± 2.8 8.7 ± 0.4 1.7 ± 0.6
T6 7.42 ± 0.03 40.6 ± 3.7 39.4 ± 11.4b 2.0 ± 0.6 26.4 ± 1.0 70.9 ± 10.2b 132 ± 3 4.9 ± 0.6 105 ± 3.4 9.1 ± 1.2 1.8 ± 0.4
T7 7.43 ± 0.02 41.8 ± 1.9 31.4 ± 3.7 3.4 ± 2.4 28.0 ± 2.2 62.7 ± 9.0 134 ± 3 5.1 ± 0.7 104 ± 3.9 9.3 ± 0.9 1.9 ± 0.2
  1. PCO2, partial pressure of carbon dioxide; PO2, partial pressure of oxygen; BE, base excess; HCO3¯, bicarbonate; SO2, oxygen saturation; AG, anion gap. T0, immediately prior to injection of digoxin; T1-T7, 1, 2, 3, 4, 24, 48 and 72 h after digoxin administration. bDiffer significantly at P < 0.05 compared to pre-injection values.