Table 2 Duration (days) after which parasitaemia developed in mice inoculated with a mixture of test substances and Trypanosoma congolense infected blood
From: Antitrypanosomal activity of aloin and its derivatives against Trypanosoma congolensefield isolate
Dose of test substance mixed with 0.02 ml of infected blood | Number of mice which developed infection | Infection interval in days (mean ± SEM) |
|---|---|---|
4.0 mg/ml E | 0/5 | Ni |
2.0 mg/ml E | 2/5 | 17.50 ± 0.50 |
0.4 mg/ml E | 4/5 | 13.75 ± 0.48 |
0.1 mg/ml E | 5/5 | 12.20 ± 0.40 |
4.0 mg/ml A | 1/5 | 26.00 |
2.0 mg/ml A | 3/5 | 16 ± 0.58 |
0.4 mg/ml A | 5/5 | 13.40 ± 0.24 |
0.1 mg/ml A | 5/5 | 11.80 ± 0.66 |
4.0 mg/ml AE | 0/5 | Ni |
2.0 mg/ml AE | 2/5 | 18.00 ± 1.00 |
0.4 mg/ml AE | 4/5 | 14.00 ± 0.40 |
0.1 mg/ml AE | 5/5 | 12.00 ± 0.54 |
4.0 mg/ml Rx | 0/5 | Ni |
2.0 mg/ml Rx | 2/5 | 19.50 ± 0.71 |
0.4 mg/ml Rx | 3/5 | 17.00 ± 0.58 |
0.1 mg/ml Rx | 5/5 | 14.20 ± 0.37 |
4.0 mg/ml DA | 0/5 | Ni |
2.0 mg/ml DA | 1/5 | 19.00 |
0.4 mg/ml DA | 3/5 | 16.33 ± 0.33 |
0.1 mg/ml DA | 5/5 | 13.40 ± 0.81 |
0.1 ml 10% DMSO | 5/5 | 11.20 ± 0.49 |