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Table 5 Univariable analysis of associations between clinical signs, physical examination findings and laboratory data and presence of peritonitis in bitches with pyometra

From: Outcome of pyometra in female dogs and predictors of peritonitis and prolonged postoperative hospitalization in surgically treated cases

Variablea

No of bitches with peritonitis/ bitches with variable n (%)

Missing data

p-value (Chi-square test/Fisher’s exact test)

Case history

Anorexia

Yes

22/166 (13)

70

0.05

 

No

4/79 (5)

  

Polyuria

Yes

17/148 (11)

65

0.34

 

No

16/102 (16)

  

Polydipsia

Yes

15/154 (10)

64

0.07

 

No

17/97 (17)

  

Vomiting

Yes

14/64 (22)

8

0.01

 

No

25/243 (10)

  

Diarrhea

Yes

8/51 (16)

8

0.5

 

No

31/256 (12)

  

Vaginal discharge

Yes

27/203 (13)

44

0.99

 

No

9/68 (13)

  

Depression

Normal (brightness)

8/119 (7)

8

< 0.0001

 

Mild

12/115 (10)

  
 

Moderate

11/54 (20)

  
 

Severe

8/19 (42)

  

Lameness

Yes

8/48 (17)

14

0.4

 

No

31/253 (12)

  

Urinary tract infection

Yes

1/19 (5)

14

0.3

 

No

38/282 (13)

  

Physical examination

Body temperature

Normal

16/170 (9)

57

0.006

 

Fever

19/81 (23)

  
 

Hypothermia

0/7 (0)

  

CRT

Normal

15/133 (11)

166

0.03

 

Abnormal

5/16 (31)

  

Mucous membranes

Normal

22/213 (10)

8

0.02

 

Pale

8/42 (19)

  
 

Hyperemic

8/51 (16)

  

Hydration status

Normal

25/224 (11)

8

0.004

 

Mild

8/67 (12)

  
 

Moderate

5/15 (33)

  
 

Severe

1/1 (100)

  

Abdominal pain

Yes

14/67 (21)

8

0.02

 

No

25/240 (10)

  

Palpable uterus

Yes

6/58 (10)

8

0.5

 

No

33/249 (18)

  

Ophthalmological exam

Ocular discharge

37/279 (13)

8

0.5

 

Conjunctivitis

2/22 (9)

  
 

Uveitis

0/6 (0)

  

Laboratory analyses

WBC

Normal

10/90 (11)

102

< 0.0001

 

Leucopenia

3/5 (62)

  
 

Leucocytosis

11/115 (10)

  

Neutrophils

Normal

9/85 (11)

110

< 0.0001

 

Neutropenia

3/5 (62)

  
 

Neutrophilia

10/112 (9)

  

Band neutrophils

Yes

18/166 (11)

118

0.07

 

Increased

7/31 (23)

  

Toxic neutrophils

Yes

4/21 (19)

102

0.3

 

No

22/192 (11)

  

Monocytes

Normal

12/90 (13)

112

0.02

 

Monocytopenia

3/7 (43)

  
 

Monocytosis

9/106 (8)

  

Hb

Normal

5/32 (16)

260

0.5

 

Dereased

4/21 (19)

  
 

Increased

1/2 (50)

  

Hct

Normal

10/85 (12)

148

0.9

 

Anemia

9/82 (11)

  

ALP

Normal

14/108 (13)

141

0.48

 

Decreased

0/4 (0)

  
 

Increased

5/62 (8)

  

Creatinine

Normal

21/202 (10)

107

0.01

 

Increased

1/5 (20)

  

Bile acid

Normal

3/23 (13)

285

0.9

 

Increased

1/7 (14)

  

BUN

Normal

5/26 (19)

285

0.63

 

Uremia

0/1 (0)

  

Glucose

Normal

16/133 (12)

173

0.05

 

Hypogycemia

2/4 (50)

  
 

Hyperglycemia

0/5 (0)

  

Lactate

Normal

4/17 (23)

296

0.4

 

Increased

1/2 (50)

  
  1. aNormal = Within the reference range (as indicated below) for healthy bitches and for laboratory variables at the Clinical chemistry laboratory, University Animal Hospital, Swedish University for Agricultural Sciences, Sweden. CRT = Capillary refill time (1–2 s), WBC = White Blood Cell Count (5.8-16.0 ×109/L), Hb = Hemoglobin (132–199 g/L), Hct = Hematocrit (38-57%), ALP = Alkaline phosphatase (<5 μkat/L), BUN = Blood urea nitrogen (2.5-8.5 mmol/L), Neutrophils (3.0-11.5 ×109/L), Monocytes (0.2-1.4 ×109/L), Creatinine (40–130 μmol/L), Bile acids (<10 μmol/L), Glucose (4.5-5.8 mmol/L, ), Lactate levels (<2.2 mmol/L), Body temperature (38–39°C).