Skip to main content

Table 5 Univariable analysis of associations between clinical signs, physical examination findings and laboratory data and presence of peritonitis in bitches with pyometra

From: Outcome of pyometra in female dogs and predictors of peritonitis and prolonged postoperative hospitalization in surgically treated cases

Variablea No of bitches with peritonitis/ bitches with variable n (%) Missing data p-value (Chi-square test/Fisher’s exact test)
Case history
Anorexia Yes 22/166 (13) 70 0.05
  No 4/79 (5)   
Polyuria Yes 17/148 (11) 65 0.34
  No 16/102 (16)   
Polydipsia Yes 15/154 (10) 64 0.07
  No 17/97 (17)   
Vomiting Yes 14/64 (22) 8 0.01
  No 25/243 (10)   
Diarrhea Yes 8/51 (16) 8 0.5
  No 31/256 (12)   
Vaginal discharge Yes 27/203 (13) 44 0.99
  No 9/68 (13)   
Depression Normal (brightness) 8/119 (7) 8 < 0.0001
  Mild 12/115 (10)   
  Moderate 11/54 (20)   
  Severe 8/19 (42)   
Lameness Yes 8/48 (17) 14 0.4
  No 31/253 (12)   
Urinary tract infection Yes 1/19 (5) 14 0.3
  No 38/282 (13)   
Physical examination
Body temperature Normal 16/170 (9) 57 0.006
  Fever 19/81 (23)   
  Hypothermia 0/7 (0)   
CRT Normal 15/133 (11) 166 0.03
  Abnormal 5/16 (31)   
Mucous membranes Normal 22/213 (10) 8 0.02
  Pale 8/42 (19)   
  Hyperemic 8/51 (16)   
Hydration status Normal 25/224 (11) 8 0.004
  Mild 8/67 (12)   
  Moderate 5/15 (33)   
  Severe 1/1 (100)   
Abdominal pain Yes 14/67 (21) 8 0.02
  No 25/240 (10)   
Palpable uterus Yes 6/58 (10) 8 0.5
  No 33/249 (18)   
Ophthalmological exam Ocular discharge 37/279 (13) 8 0.5
  Conjunctivitis 2/22 (9)   
  Uveitis 0/6 (0)   
Laboratory analyses
WBC Normal 10/90 (11) 102 < 0.0001
  Leucopenia 3/5 (62)   
  Leucocytosis 11/115 (10)   
Neutrophils Normal 9/85 (11) 110 < 0.0001
  Neutropenia 3/5 (62)   
  Neutrophilia 10/112 (9)   
Band neutrophils Yes 18/166 (11) 118 0.07
  Increased 7/31 (23)   
Toxic neutrophils Yes 4/21 (19) 102 0.3
  No 22/192 (11)   
Monocytes Normal 12/90 (13) 112 0.02
  Monocytopenia 3/7 (43)   
  Monocytosis 9/106 (8)   
Hb Normal 5/32 (16) 260 0.5
  Dereased 4/21 (19)   
  Increased 1/2 (50)   
Hct Normal 10/85 (12) 148 0.9
  Anemia 9/82 (11)   
ALP Normal 14/108 (13) 141 0.48
  Decreased 0/4 (0)   
  Increased 5/62 (8)   
Creatinine Normal 21/202 (10) 107 0.01
  Increased 1/5 (20)   
Bile acid Normal 3/23 (13) 285 0.9
  Increased 1/7 (14)   
BUN Normal 5/26 (19) 285 0.63
  Uremia 0/1 (0)   
Glucose Normal 16/133 (12) 173 0.05
  Hypogycemia 2/4 (50)   
  Hyperglycemia 0/5 (0)   
Lactate Normal 4/17 (23) 296 0.4
  Increased 1/2 (50)   
  1. aNormal = Within the reference range (as indicated below) for healthy bitches and for laboratory variables at the Clinical chemistry laboratory, University Animal Hospital, Swedish University for Agricultural Sciences, Sweden. CRT = Capillary refill time (1–2 s), WBC = White Blood Cell Count (5.8-16.0 ×109/L), Hb = Hemoglobin (132–199 g/L), Hct = Hematocrit (38-57%), ALP = Alkaline phosphatase (<5 μkat/L), BUN = Blood urea nitrogen (2.5-8.5 mmol/L), Neutrophils (3.0-11.5 ×109/L), Monocytes (0.2-1.4 ×109/L), Creatinine (40–130 μmol/L), Bile acids (<10 μmol/L), Glucose (4.5-5.8 mmol/L, ), Lactate levels (<2.2 mmol/L), Body temperature (38–39°C).