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Table 4 Univariable analysis of association between clinical signs, physical examination findings and laboratory data and the risk of prolonged postoperative hospitalization (≥ 3 days) in bitches with pyometra

From: Outcome of pyometra in female dogs and predictors of peritonitis and prolonged postoperative hospitalization in surgically treated cases

Variablea No. of bitches with prolonged hospitalization/bitches with variable n (%) Missing data p-value (Chi-square test/Fisher’s exact test)
Case history
Anorexia Yes 34/167 (20) 69 0.08
  No 9/79 (11)   
Polyuria Yes 25/151 (16) 62 0.17
  No 24/102 (23)   
Polydipsia Yes 24/159 (15) 59 0.04
  No 25/97 (16)   
Vomiting Yes 21/68 (31) 0 0.005
  No 39/247 (16)   
Diarrhea Yes 13/51 (25) 0 0.2
  No 47/264 (18)   
Vaginal discharge Yes 44/205 (21) 42 0.5
  No 12/68 (18)   
Depression Normal (brightness) 12/126 (9) 0 < 0.0001
  Mild 20/116 (17)   
  Moderate 15/54 (28)   
  Severe 13/19 (68)   
Lameness Yes 13/48 (27) 14 0.11
  No 44/253 (17)   
Urinary tract infection Yes 3/19 (16) 14 0.7
  No 54/282 (19)   
Physical examination
Body temperature Normal 31/175 (18) 50 0.4
  Fever 20/82 (24)   
  Hypothermia 1/8 (12)   
CRT Normal 25/133 (19) 165 0.11
  Abnormal 6/17 (35)   
Mucous membranes Normal 35/220 (16) 0 0.01
  Pale 14/43 (33)   
  Hyperemic 10/51 (20)   
  Toxic 1/1 (100)   
Hydration status Normal 37/232 (16) 0 0.004
  Mild 15/67 (22)   
  Moderate 7/15 (47)   
  Severe 1/1 (100)   
Abdominal pain Yes 20/69 (29) 0 0.02
  No 40/246 (16)   
Palpable uterus Yes 13/59 (22) 0 0.5
  No 47/256 (18)   
Ophthalmological exam Ocular discharge 56/287 (19) 0 0.48
  Conjunctivitis 4/22 (18)   
  Uveitis 0/6 (0)   
Laboratory analyses
WBC Normal 21/90 (23) 102 < 0.0001
  Leucocytopenia 7/8 (87)   
  Leucocytosis 16/115 (14)   
Neutrophils Normal 19/85 (22) 110 < 0.0001
  Neutropenia 7/8 (87)   
  Neutrophilia 15/112 (13)   
Band neutrophils Normal 33/166 (20) 118 0.25
  Increased 9/31 (29)   
Toxic neutrophils Yes 7/21 (33) 102 0.1
  No 37/192 (19)   
Monocytes Normal 23/90 (26) 112 0.0004
  Monocytopenia 5/7 (71)   
  Monocytosis 14/106 (13)   
Hb Normal 9/32 (28) 260 0.7
  Low 5/21 (24)   
  High 1/2 (50)   
Hct Normal 15/85 (18) 148 0.38
  Anemia 19/82 (23)   
ALP Normal 17/113 (15) 134 0.48
  Decreased 1/4 (25)   
  Increased 14/64 (22)   
Creatinine Normal 35/209 (17) 100 0.0009
  Increased 4/6 (67)   
Bile acids Normal 4/23 (17) 285 0.5
  Increased 2/7 (29)   
BUN Normal 5/26 (19) 288 0.09
  Uremia 1/1 (100)   
Glucose Normal 24/137 (17) 167 0.01
  Hypoglycemia 4/6 (67)   
  Hyperglycemia 1/5 (20)   
Lactate Normal 4/17 (23) 296 0.03
  Increased 2/2 (100)   
  1. aNormal = Within the reference range (as indicated below) for healthy bitches and for laboratory variables at the main Clinical chemistry laboratory, University Animal Hospital, Swedish University for Agricultural Sciences, Sweden. CRT = Capillary refill time (1–2 s), WBC = White Blood Cell Count (5.8-16.0 ×109/L), Hb = Hemoglobin (132–199 g/L), Hct = Hematocrit (38-57%), ALP = Alkaline phosphatase (<5.0 μkat/L), BUN = Blood urea nitrogen (2.5-8.5 mmol/L), Neutrophils (3.0-11.5 ×109/L), Monocytes (0.2-1.4 x109/L), Creatinine (40–130 μmol/L), Bile acids (<10 μmol/L), Glucose (4.5-5.8 mmol/L), Lactate levels (<2.2 mmol/L), Body temperature (38–39.2°C).