|
Variablea
|
No. of bitches with prolonged hospitalization/bitches with variable n (%)
|
Missing data
|
p-value (Chi-square test/Fisher’s exact test)
|
|---|
|
Case history
|
|
Anorexia
|
Yes
|
34/167 (20)
|
69
|
0.08
|
| |
No
|
9/79 (11)
| | |
|
Polyuria
|
Yes
|
25/151 (16)
|
62
|
0.17
|
| |
No
|
24/102 (23)
| | |
|
Polydipsia
|
Yes
|
24/159 (15)
|
59
|
0.04
|
| |
No
|
25/97 (16)
| | |
|
Vomiting
|
Yes
|
21/68 (31)
|
0
|
0.005
|
| |
No
|
39/247 (16)
| | |
|
Diarrhea
|
Yes
|
13/51 (25)
|
0
|
0.2
|
| |
No
|
47/264 (18)
| | |
|
Vaginal discharge
|
Yes
|
44/205 (21)
|
42
|
0.5
|
| |
No
|
12/68 (18)
| | |
|
Depression
|
Normal (brightness)
|
12/126 (9)
|
0
|
< 0.0001
|
| |
Mild
|
20/116 (17)
| | |
| |
Moderate
|
15/54 (28)
| | |
| |
Severe
|
13/19 (68)
| | |
|
Lameness
|
Yes
|
13/48 (27)
|
14
|
0.11
|
| |
No
|
44/253 (17)
| | |
|
Urinary tract infection
|
Yes
|
3/19 (16)
|
14
|
0.7
|
| |
No
|
54/282 (19)
| | |
|
Physical examination
|
|
Body temperature
|
Normal
|
31/175 (18)
|
50
|
0.4
|
| |
Fever
|
20/82 (24)
| | |
| |
Hypothermia
|
1/8 (12)
| | |
|
CRT
|
Normal
|
25/133 (19)
|
165
|
0.11
|
| |
Abnormal
|
6/17 (35)
| | |
|
Mucous membranes
|
Normal
|
35/220 (16)
|
0
|
0.01
|
| |
Pale
|
14/43 (33)
| | |
| |
Hyperemic
|
10/51 (20)
| | |
| |
Toxic
|
1/1 (100)
| | |
|
Hydration status
|
Normal
|
37/232 (16)
|
0
|
0.004
|
| |
Mild
|
15/67 (22)
| | |
| |
Moderate
|
7/15 (47)
| | |
| |
Severe
|
1/1 (100)
| | |
|
Abdominal pain
|
Yes
|
20/69 (29)
|
0
|
0.02
|
| |
No
|
40/246 (16)
| | |
|
Palpable uterus
|
Yes
|
13/59 (22)
|
0
|
0.5
|
| |
No
|
47/256 (18)
| | |
|
Ophthalmological exam
|
Ocular discharge
|
56/287 (19)
|
0
|
0.48
|
| |
Conjunctivitis
|
4/22 (18)
| | |
| |
Uveitis
|
0/6 (0)
| | |
|
Laboratory analyses
|
|
WBC
|
Normal
|
21/90 (23)
|
102
|
< 0.0001
|
| |
Leucocytopenia
|
7/8 (87)
| | |
| |
Leucocytosis
|
16/115 (14)
| | |
|
Neutrophils
|
Normal
|
19/85 (22)
|
110
|
< 0.0001
|
| |
Neutropenia
|
7/8 (87)
| | |
| |
Neutrophilia
|
15/112 (13)
| | |
|
Band neutrophils
|
Normal
|
33/166 (20)
|
118
|
0.25
|
| |
Increased
|
9/31 (29)
| | |
|
Toxic neutrophils
|
Yes
|
7/21 (33)
|
102
|
0.1
|
| |
No
|
37/192 (19)
| | |
|
Monocytes
|
Normal
|
23/90 (26)
|
112
|
0.0004
|
| |
Monocytopenia
|
5/7 (71)
| | |
| |
Monocytosis
|
14/106 (13)
| | |
|
Hb
|
Normal
|
9/32 (28)
|
260
|
0.7
|
| |
Low
|
5/21 (24)
| | |
| |
High
|
1/2 (50)
| | |
|
Hct
|
Normal
|
15/85 (18)
|
148
|
0.38
|
| |
Anemia
|
19/82 (23)
| | |
|
ALP
|
Normal
|
17/113 (15)
|
134
|
0.48
|
| |
Decreased
|
1/4 (25)
| | |
| |
Increased
|
14/64 (22)
| | |
|
Creatinine
|
Normal
|
35/209 (17)
|
100
|
0.0009
|
| |
Increased
|
4/6 (67)
| | |
|
Bile acids
|
Normal
|
4/23 (17)
|
285
|
0.5
|
| |
Increased
|
2/7 (29)
| | |
|
BUN
|
Normal
|
5/26 (19)
|
288
|
0.09
|
| |
Uremia
|
1/1 (100)
| | |
|
Glucose
|
Normal
|
24/137 (17)
|
167
|
0.01
|
| |
Hypoglycemia
|
4/6 (67)
| | |
| |
Hyperglycemia
|
1/5 (20)
| | |
|
Lactate
|
Normal
|
4/17 (23)
|
296
|
0.03
|
| |
Increased
|
2/2 (100)
| | |
- aNormal = Within the reference range (as indicated below) for healthy bitches and for laboratory variables at the main Clinical chemistry laboratory, University Animal Hospital, Swedish University for Agricultural Sciences, Sweden. CRT = Capillary refill time (1–2 s), WBC = White Blood Cell Count (5.8-16.0 ×109/L), Hb = Hemoglobin (132–199 g/L), Hct = Hematocrit (38-57%), ALP = Alkaline phosphatase (<5.0 μkat/L), BUN = Blood urea nitrogen (2.5-8.5 mmol/L), Neutrophils (3.0-11.5 ×109/L), Monocytes (0.2-1.4 x109/L), Creatinine (40–130 μmol/L), Bile acids (<10 μmol/L), Glucose (4.5-5.8 mmol/L), Lactate levels (<2.2 mmol/L), Body temperature (38–39.2°C).
