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Table 1 Correlation between the three antibody stains with the clinic and pathologic factors of the female dogs

From: Expression of glutathione, glutathione peroxidase and glutathione S-transferase pi in canine mammary tumors

Clinical and pathologic factors Number of bitches GSH GSTpi GSH-Px
Age     
  ≥ 10 years 16 (53.3%) 185.3 ± 6.532 202.8 ± 2.537 194.4 ± 3.838
  < 10 years 14 (46.7%) 196.9 ± 6.170 206.5 ± 1.842 202.3 ± 2.936
  P   > 0.05 > 0.05 > 0.05
Time course     
  Until 6 months 13 (50%) 196.5 ± 21.82 204.6 ± 6.172 202.9 ± 13.81
  Between 6 and 18 months 7 (27%) 182.3 ± 31.20 205.5 ± 9.397 192.5 ± 13.55
  More than 18 months 6 (23%) 180.0 ± 24.07 202.5 ± 14.49 190.8 ± 14.18
  P   > 0.05# > 0.05# > 0.05#
Histological type     
  Malignant tumors 26 (87%) 189.9 ± 4.829 204.0 ± 1.757 198.3 ± 2.869
  Benign 4 (13%) 196.3 ± 15.69 209.3 ± 3.860 203.5 ± 4.173
  P   > 0.05 > 0.05 > 0.05
Clinical staging     
  I 11 (37%) 202.3 ± 15.36 204.7 ± 5.746 199.4 ± 11.83
  II 4 (13%) 190.0 ± 45.03 208.0 ± 4.243 198.3 ± 19.57
  III 10 (33%) 183.3 ± 24.50 202.2 ±12.75 196.4 ± 13.09
  IV 5 (17%) 180.6 ± 21.13 206.0 ± 8.689 198.4 ± 18.94
  P   > 0.05# > 0.05# > 0.05#
Number of nodules     
  Multiples 9 (30%) 177.9 ± 7.181 204.6 ± 2.844 200.8 ± 5.112
  Single 21 (70%) 196.2 ± 5.314 204.5 ± 2.001 197.4 ± 3.044
  P   > 0.05 > 0.05 > 0.05
Tumor ulcerated     
  Ulceration 10 (34%) 180.8 ± 22.75 203.5 ± 13.53 205.0 ± 9.129
  Necrosis 2 (7%) 162.0 ± 55.15 204.9 ± 5.557 189.5 ± 6.364
  Absent 17 (59%) 199.4 ± 19.52 206.0 ± 8.485 195.2 ± 15.34
  P   0.03* # > 0.05# > 0.05#
Tumor vascularization     
  Abundant 15 (50%) 184.1 ± 7.164 205.7 ± 2.080 197.9 ± 3.349
  Moderate 15 (50%) 197.3 ± 5.374 203.3 ± 2.499 198.2 ± 3.914
  P   > 0.05 > 0.05 > 0.05
Censure     
  Death 8 (26.7%) 165.5 ± 8.592 204.1 ± 1.869 203.0 ± 3.937
  Living 22 (73,3%) 199.9 ± 3.921 205.9 ± 1.191 196.3 ± 3.099
  P   0.0003* > 0.05 > 0.05
Metastasis     
  Yes 8 (26.7%) 165.5 ± 8.592 204.1 ± 1.869 203.0 ± 3.937
  No 22 (73.3%) 199.9 ± 3.921 205.9 ± 1.191 196.3 ± 3.099
  P   0.0003* > 0.05 > 0.05
  1. *Significant value to Student’s t test # ANOVA test.