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Figure 4 | BMC Veterinary Research

Figure 4

From: A recombinant chimera comprising the R1 and R2 repeat regions of M. hyopneumoniae P97 and the N-terminal region of A. pleuropneumoniaeApxIII elicits immune responses

Figure 4

Cytokine profiles of splenocytes obtained from immunized mice. Mice were primed with Ap97, ApxN, or P97C vaccines. Splenocytes were isolated from each mouse and then re-stimulated with Ap97, ApxN, or P97C dissolved in PBS. At the end of re-stimulation, cell culture supernatants were analyzed for IFN-γ (A) and IL-4 (B). Data represent the mean ± SD (n = 4). *P < 0.05 and **P < 0.01, significantly different from the corresponding PBS-treated controls (paired t-test).

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