Skip to main content

Table 1 Antiproliferative activity of VDC-1101 and its metabolites in human multiple myeloma cell lines

From: GS-9219/VDC-1101 - a prodrug of the acyclic nucleotide PMEG has antitumor activity inspontaneous canine multiple myeloma

 

Calculated IC50(μM)

 

H-929

RPMI-8226

U-266

PMEG

1.9 ± 0.6

0.2 ± 0.04

1.0 ± 0.3

cPrPMEDAP

1.8 ± 0.5

0.2 ± 0.06

0.7 ± 0.2

VDC-1101

0.6 ± 0.2

0.34 ± 0.05

0.6 ± 0.2

Back to article page

BMC Veterinary Research

ISSN: 1746-6148

Contact us