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Figure 1 | BMC Veterinary Research

Figure 1

From: Polymorphisms within the Telomerase Reverse Transcriptase gene (TERT) in four breeds of dogs selected for difference in lifespan and cancer susceptibility

Figure 1

Representative polymorphisms in the canine TERT gene. (a) – Exon 17 of the TERT gene, displaying polymorphisms at 19289, 19298 and 19299. Location 19298 displays heterozygous polymorphisms, but no variant homozygous polymorphisms. Using the IUPAC nucleotide code, in this context “S” designates a locus that is heterozygous for G and C and “M” designates a locus that is heterozygous for A and C. (b) – Chromatogram of region displayed in part (a), corresponding to “Irish Wolfhound 5 (IW5).” The dual peak contributing to the “S” heterozygous polymorphism is marked. (c) – An intronic region of the TERT gene, displaying polymorphisms at 17268, 17273, and 17275. These locations display heterozygous polymorphisms, but no variant homozygous polymorphisms; location 17268 is shown in the chromatogram in part (d). (d) – Chromatogram of region displayed in part (c), corresponding to “Dachshund 2 (DH2).” The dual peak contributing to the “S” heterozygous polymorphism is marked.

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BMC Veterinary Research

ISSN: 1746-6148

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