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Table 2 Subjective scoring of TKR immunoreactivity in cpAC biospecimens from 12 dogs

From: Canine pulmonary adenocarcinoma tyrosine kinase receptor expression and phosphorylation

TKR No staining n(%) 0 n(%) 1 n(%) 2 n(%) 3 n(%) Stromal staining n(%) Predominant localization Stained areas
EGFR 0 2 (17) 3 (25) 4 (33) 3 (25) 0 C C, M
VEGFR2 6 (50) 5 (42) 0 1 (8) 0 0 C C, M
VEGF 0 1 (8) 6 (50) 2 (17) 3 (25) 2 (17) C C, S, N
c-KIT 9 (75) 1 (8) 2 (17) 0 0 0 C C, M
PDGFRα 0 0 1 (8) 2 (17) 9 (75) 2 (17) C, N C, S, N
PDGFRβ 1 (8) 1 (8) 4 (33) 3 (25) 1 (8) 11 (92) C, S C, S, M
  1. Result numbers (n) and percentages (%) represent number of cpAC- affected dogs. Percentage of neoplastic cells staining positive were scored as follows: 1-5% = 0, 5-25% = 1 26-50% = 2 and >50% = 3. C: cytoplasmic, M: membranous, N: nuclear, S: stromal. No staining represents number and percentage of cpAC-affected dogs that have no evidence of any positive immunoreactivity.