Skip to main content

Table 2 Subjective scoring of TKR immunoreactivity in cpAC biospecimens from 12 dogs

From: Canine pulmonary adenocarcinoma tyrosine kinase receptor expression and phosphorylation

TKR

No staining n(%)

0 n(%)

1 n(%)

2 n(%)

3 n(%)

Stromal staining n(%)

Predominant localization

Stained areas

EGFR

0

2 (17)

3 (25)

4 (33)

3 (25)

0

C

C, M

VEGFR2

6 (50)

5 (42)

0

1 (8)

0

0

C

C, M

VEGF

0

1 (8)

6 (50)

2 (17)

3 (25)

2 (17)

C

C, S, N

c-KIT

9 (75)

1 (8)

2 (17)

0

0

0

C

C, M

PDGFRα

0

0

1 (8)

2 (17)

9 (75)

2 (17)

C, N

C, S, N

PDGFRβ

1 (8)

1 (8)

4 (33)

3 (25)

1 (8)

11 (92)

C, S

C, S, M

  1. Result numbers (n) and percentages (%) represent number of cpAC- affected dogs. Percentage of neoplastic cells staining positive were scored as follows: 1-5% = 0, 5-25% = 1 26-50% = 2 and >50% = 3. C: cytoplasmic, M: membranous, N: nuclear, S: stromal. No staining represents number and percentage of cpAC-affected dogs that have no evidence of any positive immunoreactivity.