Hepatic inflammation scores correlate with common carotid intima-media thickness in rats with NAFLD induced by a high-fat diet

Table 1 Biochemical changes in the blood

Group	Control	8 weeks	12 weeks	16 weeks
ALT(U/L)	39.00 ± 7.05	52.44 ± 7.92	81.11 ± 31.28	94.67 ± 44.38*
AST(U/L)	99.44 ± 14.14	107.89 ± 36.92	154.33 ± 79.80	206.56 ± 93.37*
GLU(mmol/L)	5.89 ± 0.49	5.99 ± 0.58	6.01 ± 0.59	6.9 ± 0.96*
TG(mmol/L)	0.56 ± 0.12	0.57 ± 0.10	0.59 ± 0.13	0.61 ± 0.14
TC(mmol/L)	1.76 ± 0.28	1.97 ± 0.46	2.10 ± 0.48	2.51 ± 0.59*
HDL-C(mmol/L)	0.55 ± 0.10	0.53 ± 0.09	0.47 ± 0.10	0.50 ± 0.10
LDL-C(mmol/L)	0.24 ± 0.05	0.68 ± 0.15*	0.83 ± 0.30*	1.21 ± 0.31*
Insulin(μIU/ml)	22.04 ± 7.46	25.93 ± 9.58	28.26 ± 9.45	36.23 ± 9.28*
HOMA _IR	5.81 ± 2.04	6.89 ± 2.54	7.51 ± 2.29	11.34 ± 4.17*

Data are mean ± SD, for 9 animals per group. *P < 0.05 vs Control. The control in table imply the control group (a standard diet) of 16 weeks. ALT, alanine aminotransferase; AST, aspartate aminotransferase; GLU, blood glucose; TG, triglyceride; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; HOMA_IR, homeostasis model assessment insulin resistance index.

ISSN: 1746-6148