Figure 3
Ultrasound and histological findings of the carotid artery and the aortas in rats. (A) Ultrasound findings of the carotid artery and the aortas from rats fed a high-fat diet for 8, 12 and 16 weeks, respectively. (B) The IMT and hemodynamic parameters such as the end-diastolic velocity, the systolic peak velocity of the carotid artery and the aortas in rats fed with a high-fat diet for 8, 12 and 16 weeks,were measured by ultrasonography. (C) H&E staining of the carotid artery and the aortas sections (objective lens, ×20). The carotid artery and the aortas in rats fed with a high-fat diet for 12 and 16 weeks show mild intimal thickening and cellular hypertrophy in the intima and media of the carotid artery and the aortas. (D) IMT of the HE stained carotid artery and abdominal aorta was measured and quantified. Results represent medians (25/75th percentiles) of 9 rats per group. *P < 0.05 vs. the control group.