Skip to main content
Figure 1 | BMC Veterinary Research

Figure 1

From: Biologic activity of the novel orally bioavailable selective inhibitor of nuclear export (SINE) KPT-335 against canine melanoma cell lines

Figure 1

KPT-335 inhibits proliferation of canine melanoma cells. Canine melanoma cell lines were treated with DMSO or KPT-335 at increasing concentrations for 96 hours then analyzed using the CyQUANT® cell proliferation kit. Proliferation values are listed as a percentage of DMSO control. Experiments were performed in triplicate and repeated three times. For each cell line there was a significant decreasing trend in cell proliferation with dose of KPT-335 (p < 0.0001).

Back to article page