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Table 1 Comparison of gross and histopathological lesion frequency in CTRL and INOC groups

From: Confirmation that “Brachyspira hampsonii” clade I (Canadian strain 30599) causes mucohemorrhagic diarrhea and colitis in experimentally infected pigs

  

Pvalue

Description

 

CTRL (n = 6)

INOC (n = 11)

INOC (with MHD) (n = 9)

INOC vs. CTRL

INOC (with MHD) vs. CTRL

Gross pathology frequency*

     
 

Proximal colon

1/6

8/11

8/9

0.04

0.01

 

Apex colon

0/6

9/11

9/9

<0.01

<0.001

 

Distal colon

0/6

7/11

7/9

0.02

<0.01

 

Cecum

1/6

6/11

5/9

ns

ns

 

Rectum

0/6

5/11

5/9

0.08

0.04

Histopathologic lesion frequency**

    
 

Colonic inflammation

0/6

9/11

9/9

<0.01

<0.001

 

Colonic necrosis

0/6

9/11

9/9

<0.01

<0.001

 

Cecal inflammation

0/6

6/11

6/9

0.04

0.001

 

Cecal necrosis

0/6

3/11

3/9

ns

0.02

 

Colonic spirochetes

0/6

8/11

8/9

<0.01

0.001

  1. *Gross lesions include mucosal edema, hyperemia, congestion, with multifocal to diffuse mucofibrinonecrotic exudate.
  2. **Histopathological lesions and colonic spirochete scores graded 0 to 3 reflecting negative, mild, moderate and severe inflammation or necrosis. Scores greater than 1 were considered lesional.