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Table 2 Protein identification of differentially expressed proteins

From: Identification of serum biomarkers in dogs naturally infected with Babesia canis canis using a proteomic approach

Protein name Accession numbera Number of unique peptidesb Sequence coverage (%)b Mascot scoreb Biological function Spot no.c
Alpha-1-acid glycoprotein gi|345777714 25 53 628 Acute phase response 596, 579
Apolipoprotein A-I gi|73955106 70 72 1834 Cholesterol, lipid and steroid metabolism 869, 432
Lipid transport
Antithrombin-III gi|359320010 5 19 161 Blood coagulation 432
Vitamin D-binding protein gi|73975215 24 57 543 Vitamin D metabolic process 432
Apolipoprotein A-IV gi|345799905 66 72 1401 Removal of superoxide radicals 590
Lipid metabolism
Complement C3 gi|359322249 16 15 356 Complement activation (classical and alternative pathway) 590
Inflammatory response
Serotransferrin gi|73990142 25 40 672 Cellular iron ion homeostasis 327
Iron ion transport
Hemopexin gi|73988725 12 44 273 Cellular iron ion homeostasis 327
Alpha-2-HS-glycoprotein gi|359323766 7 40 273 Acute phase response 596, 432
Haptoglobin gi|123511 5 41 159 Cellular iron ion homeostasis 579
Acute phase response
Alpha-2-antiplasmin gi|345805038 3 13 101 Acute phase response 327
Fibrinolysis
Clusterin gi|50979240 31 25 864 Apoptosis 596, 579
Complement pathway
Leucine-rich-α2-glycoprotein gi|73987375 24 50 625 Acute phase response 432
Zinc-alpha-2-glycoprotein gi|73958037 15 46 310 Immune response 579
Immunoglobulin gamma heavy chain B gi|17066526 12 27 206 Immune response 432
Complement activation
Immunoglobulin gamma heavy chain C gi|17066528 10 20 222 Immune response 432
IgA heavy chain constant region gi|598107 7 22 124 Immune response 327
  1. aAccesion number from NCBI Genbank database for Canis lupus familiaris.
  2. bData are representatives of four separate experimental group.
  3. cNumber refer to protein spots indicated in Figure 1.