Musculoskeletal disorders and orthopaedics

Section edited by Ignacio Calvo

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  1. Research article

    FOXO1, PXK, PYCARD and SAMD9L are differentially expressed by fibroblast-like cells in equine synovial membrane compared to joint capsule

    The synovial membrane lines the luminal side of the joint capsule in synovial joints. It maintains joint homeostasis and plays a crucial role in equine joint pathology. When trauma or inflammation is induced i...

    Line Nymann Thomsen, Preben Dybdahl Thomsen, Alison Downing, Richard Talbot and Lise Charlotte Berg

    BMC Veterinary Research 2017 13:106

    Published on: 14 April 2017

  2. Research article

    The effect of intra-articular botulinum toxin A on substance P, prostaglandin E2, and tumor necrosis factor alpha in the canine osteoarthritic joint

    Recently, intra-articular botulinum toxin A (IA BoNT A) has been shown to reduce joint pain in osteoarthritic dogs. Similar results have been reported in human patients with arthritis. However, the mechanism o...

    Helka M. Heikkilä, Anna K. Hielm-Björkman, John F. Innes and Outi M. Laitinen-Vapaavuori

    BMC Veterinary Research 2017 13:74

    Published on: 21 March 2017

  3. Research article

    The magnitude of muscular activation of four canine forelimb muscles in dogs performing two agility-specific tasks

    The purpose of this study was to measure the muscular activation in four forelimb muscles while dogs performed agility tasks (i.e., jumping and A-frame) and to provide insight into potential relationships betw...

    Kimberley L. Cullen, James P. Dickey, Stephen H. M. Brown, Stephanie G. Nykamp, Leah R. Bent, Jeffrey J. Thomason and Noël M. M. Moens

    BMC Veterinary Research 2017 13:68

    Published on: 7 March 2017

  4. Research article

    A prospective follow up of age related changes in the subchondral bone density of the talus of healthy Labrador Retrievers

    During growth, the skeletal structures adapt to the increased loading conditions and mature to a fully-grown skeleton. Subchondral bone density reflects the effect of long-term joint loading and it is expected...

    W. Dingemanse, M. Müller-Gerbl, I. Jonkers, J. Vander Sloten, H. van Bree and I. Gielen

    BMC Veterinary Research 2017 13:57

    Published on: 20 February 2017

  5. Research article

    Monitoring training response in young Friesian dressage horses using two different standardised exercise tests (SETs)

    Most Friesian horses reach their anaerobic threshold during a standardized exercise test (SET) which requires lower intensity exercise than daily routine training. Aim: to study strengths and weaknesses of an ...

    Cornelis Marinus de Bruijn, Willem Houterman, Margreet Ploeg, Bart Ducro, Berit Boshuizen, Klaartje Goethals, Elisabeth-Lidwien Verdegaal and Catherine Delesalle

    BMC Veterinary Research 2017 13:49

    Published on: 14 February 2017

  6. Research article

    The method of attachment influences accelerometer-based activity data in dogs

    Accelerometer-based activity monitoring is a promising new tool in veterinary medicine used to objectively assess activity levels in dogs. To date, it is unknown how device orientation, attachment method, and ...

    Kyle W. Martin, Anastasia M. Olsen, Colleen G. Duncan and Felix M. Duerr

    BMC Veterinary Research 2017 13:48

    Published on: 10 February 2017

  7. Research article

    Pilot evaluation of a novel unilateral onychectomy model and efficacy of an extended release buprenorphine product

    Non-steroidal anti-inflammatory drugs (NSAIDs), transdermal fentanyl patches, and transmucosal buprenorphine are probably the most commonly used options for providing post-operative analgesia in the early at-h...

    Masataka Enomoto, Patricia D. Kigin, David Bledsoe, Robyn Slone, Jonathan Hash, Charles E. Smith and B. Duncan X. Lascelles

    BMC Veterinary Research 2017 13:32

    Published on: 24 January 2017

  8. Case Report

    A case of cranium bifidum with meningocele in Ayrshire calf

    Congenital cranial bone defects predispose to herniation of meninges, sometimes with brain tissue involvement, to form a cerebrospinal fluid (CSF)–filled cyst in the head. Such defects mainly results from foca...

    Mosiany Letura Kisipan, Caleb Oburu Orenge, David Njogu Gacheru and Raphael Muchangi Ngure

    BMC Veterinary Research 2017 13:20

    Published on: 13 January 2017

  9. Research article

    Effect of proximal translation of the osteotomized tibial tuberosity during tibial tuberosity advancement on patellar position and patellar ligament angle

    Cranial cruciate ligament insufficiency is a common orthopaedic problem in canine patients. This cadaveric and radiographic study was performed with the aim of determining the effect of proximal translation of...

    Jack D. Neville-Towle, Mariano Makara, Kenneth A. Johnson and Katja Voss

    BMC Veterinary Research 2017 13:18

    Published on: 9 January 2017

  10. Research article

    Radiographic evaluation of early periprosthetic acetabular bone contrast and prosthetic head acetabular coverage after uncemented and cemented total hip prosthesis in dogs

    Coxofemoral osteoarthritis is a chronic, disabling condition affecting people and dogs, with THA providing an excellent return to function in severely affected joints. The principal role of THA is to restore a...

    Ayman A. Mostafa, Karin Lucas, Ingo Nolte and Patrick Wefstaedt

    BMC Veterinary Research 2016 12:271

    Published on: 3 December 2016

  11. Research article

    Normal patellofemoral kinematic patterns during daily activities in dogs

    Patellar abnormalities are a common cause of pain and lameness in dogs; however, in vivo the relative motion between the femur and patella in dogs is not well described. The objective of this study was to defi...

    Erica J. Moore, Stanley E. Kim, Scott A. Banks, Antonio Pozzi, Jason D. Coggeshall and Stephen C. Jones

    BMC Veterinary Research 2016 12:262

    Published on: 25 November 2016

  12. Research article

    Pro-inflammatory cytokines and structural biomarkers are effective to categorize osteoarthritis phenotype and progression in Standardbred racehorses over five years of racing career

    Joint impact injuries initiate a progressive articular damage finally leading to post-traumatic osteoarthritis (PTOA). Racehorses represent an ideal, naturally available, animal model of the disease. Standardb...

    Andrea Bertuglia, Eleonora Pagliara, Elena Grego, Alessandro Ricci and Nika Brkljaca-Bottegaro

    BMC Veterinary Research 2016 12:246

    Published on: 8 November 2016

  13. Research article

    Effect of intraarticular inoculation of mesenchymal stem cells in dogs with hip osteoarthritis by means of objective force platform gait analysis: concordance with numeric subjective scoring scales

    Subjective pain assessment scales have been widely used for assessing lameness in response to pain, but the accuracy of these scales has been questioned. To assess scale accuracy, 10 lame, presa Canario dogs w...

    Jose M. Vilar, Belen Cuervo, Monica Rubio, Joaquín Sopena, Juan M. Domínguez, Angelo Santana and Jose M. Carrillo

    BMC Veterinary Research 2016 12:223

    Published on: 7 October 2016

  14. Research article

    In vitro effects of platelet-rich gel supernatants on histology and chondrocyte apoptosis scores, hyaluronan release and gene expression of equine cartilage explants challenged with lipopolysaccharide

    Platelet-rich plasma (PRP) preparations are a common treatment in equine osteoarthritis (OA). However, there are controversies regarding the ideal concentration of platelets and leukocytes in these biological ...

    Jorge U. Carmona, Diana L. Ríos, Catalina López, María E. Álvarez, Jorge E. Pérez and Mabel E. Bohórquez

    BMC Veterinary Research 2016 12:135

    Published on: 1 July 2016

  15. Research article

    The effect of strontium ranelate on the healing of a fractured ulna with bone gap in rabbit

    Fracture healing in bone gap is one of the major challenges encountered in Orthopedic Surgery. At present, the treatment includes bone graft, employing either internal or external fixation which has a signific...

    Mohd Rafiq Mohd Ibrahim, Simmrat Singh, Azhar Mahmood Merican, Hanumantha Rao Balaji Raghavendran, Malliga Raman Murali, Sangeetha Vasudevaraj Naveen and Tunku Kamarul

    BMC Veterinary Research 2016 12:112

    Published on: 16 June 2016

  16. Case report

    Clinicopathological findings in horses with a bi- or tripartite navicular bone

    Navicular bone partition is a rare condition reported in horses, which is during the evaluation of a lameness or prepurchase examination often misinterpreted for a parasagittal fracture. In this report, the cl...

    Ellen J. van der Zaag, Erik A. W. S. Weerts, Antoon J. M. van den Belt and Willem Back

    BMC Veterinary Research 2016 12:74

    Published on: 9 April 2016

  17. Research article

    Inflammatory response to the administration of mesenchymal stem cells in an equine experimental model: effect of autologous, and single and repeat doses of pooled allogeneic cells in healthy joints

    Mesenchymal stem cells (MSCs) transplantation has become a promising therapeutic choice for musculoskeletal injuries. Joint-related disorders are highly prevalent in horses. Therefore, these animals are consid...

    N. Ardanaz, F. J. Vázquez, A. Romero, A. R. Remacha, L. Barrachina, A. Sanz, B. Ranera, A. Vitoria, J. Albareda, M. Prades, P. Zaragoza, I. Martín-Burriel and C. Rodellar

    BMC Veterinary Research 2016 12:65

    Published on: 31 March 2016

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