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Table 2 Cardiovascular variables pre- and post- weight reduction for the cats that achieved target weight reduction

From: The effect of obesity and subsequent weight reduction on cardiac morphology and function in cats

Variable

Number of cats

Before weight reduction

After weight reduction

P value

r value

Median

(IQR)

Median

(IQR)

ECG heart rate (bpm)

11

180

160–200

180

160–200

0.932

0.26

Heart rate variability (VVTI)

11

5.24

4.96–5.72

4.87

4.56–6.00

0.790

0.08

SBP (mmHg)

10

134

116–150

129

120–157

0.438

0.26

Hs-cTnI (ng/mL)

7

0.007

0.004–0.040

0.005

0.004–0.011

0.461

0.28

NT-proBNP (pmol/L)

7

24.0

23.9–31.0

23.9

23.9–75.0

0.144

0.55

LA/Ao

10

1.3

1.26–1.46

1.41

1.27–1.57

0.386

0.26

LADmax (mm)

10

15.6

14.4–16.1

15.5

14.2–16.3

0.646

0.14

Max-IVSd (mm)

11

6.3

5.8–6.6

5.9

5.5–6.8

0.142

0.35

Max-IVSd (mm) excluding 1 HCM case

10

6.4

5.7–6.8

5.9

5.2–6.7

0.047

0.63

Max-LVFWd (mm)

11

5.5

5.1–6.0

5.3

4.9–5.8

0.045

0.60

Max-LVFWd (mm) excluding 1 HCM case

10

5.7

5.2–6.4

5.3

4.6–5.8

0.019

0.74

E velocity (m/s)

10

0.64

0.58–0.70

0.64

0.49–0.70

0.083

0.52

MV E/A

6

1.01

0.85–1.24

1.02

0.88–1.29

0.309

0.38

IVRT (ms)

10

59.0

53.0–63.0

56.0

51.0–62.0

0.859

0.05

Septal (IVS) E’/A’

9

0.60

0.55–0.82

0.75

0.58–0.98

0.085

0.57

Lateral (LVFW) E’/A’

9

0.86

0.61–1.34

1.2

0.77–1.53

0.012

0.89

Right E’/A’

9

0.86

0.56–0.78

0.66

0.52–0.80

0.766

0.10

Septal (IVS) S’ (cm/s)

10

7.15

4.83–9.33

7.4

5.60–8.40

0.646

0.15

Lateral (LVFW) S’ (cm/s)

10

7.20

5.53–10.03

6.50

5.20–7.80

0.139

0.47

Fractional shortening (%)

10

53.0

44.0–61.0

50.0

40.0–53.0

0.182

0.40

  1. The r value reflects effect size
  2. E’/A’ pulsed wave tissue Doppler imaging derived diastolic myocardial E and A wave velocity ratio, ECG Electrocardiography, hs-cTnI High sensitivity cardiac troponin I, IQR Interquartile range, IVRT isovolumetric relaxation time, IVSd end-diastolic interventricular septum thickness, LA/Ao left atrium to aorta ratio, LADmax Maximal left atrial diameter, LVFWd End-diastolic left ventricular free wall thickness, MV E/A Mitral valve E and A wave velocity ratio, NT-proBNP N-type N-terminal pro-brain natriuretic peptide, S’ Pulsed wave tissue Doppler imaging derived myocardial systolic velocity, SBP Systolic blood pressure, VVTI Vasovagal tonus index