Table 4 Biochemical parameters at pre-enrollment, 2 weeks after starting capecitabine, and 5 weeks after starting capecitabine. Bold numbers refer to values outside of the reference interval. Canine biochemical parameters at pre-enrollment, 2 weeks after starting capecitabine, and 5 weeks after starting capecitabine
Dog 1 | Dog 2 | Dog 3 | Dog 4 | Dog 5 | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Parameter | Normal range | Pre-enrollment | 2 weeks | 5 weeks | Pre-enrollment | 2 weeks | 5 weeks | Pre-enrollment | 2 weeks | 5 weeks | Pre-enrollment | 2 weeks | 5 weeks | Pre-enrollment | 2 weeks | 5 weeks |
ALT | 0-100 U/L | 31 | 62 | 31 | 60 | 54 | 46 | 87 | 78 | 91 | 303 | 319 | 345 | 84 | 55 | 77 |
ALP | 0-96 U/L | 46 | 52 | 50 | 186 | 113 | 110 | 137 | 107 | 95 | 2064 | 2166 | 2272 | 95 | 61 | 55 |
Cholesterol | 134-359 mg/dL | 234 | 217 | 204 | 257 | 275 | 287 | 272 | 312 | 321 | 244 | 280 | 312 | 326 | 284 | 308 |
BUN | 9-26 mg/dL | 31 | 34 | 39 | 19 | 20 | 21 | 17 | 17 | 18 | 27 | 14 | 17 | 36 | 47 | 78 |
Creatinine | 0.8-1.6 mg/dL | 1.6 | 1.6 | 1.7 | 0.8 | 0.9 | 1.1 | 0.9 | 1.1 | 1.2 | 1.0 | 0.6 | 0.9 | 1.4 | 1.4 | 2.3 |
Glucose | 66-123 mg/dL | 95 | 109 | 92 | 103 | 111 | 118 | 106 | 104 | 101 | 121 | 116 | 107 | 123 | 111 | 122 |
Total Protein | 5.5-7.5 mg/dL | 6.1 | 5.7 | 6.2 | 6.8 | 6.5 | 6.6 | 6.9 | 6.6 | 6.9 | 7.9 | 7.4 | 7.4 | 6.1 | 6.2 | 6.4 |
Albumin | 2.9-3.8 mg/dL | 2.7 | 2.5 | 2.7 | 3.1 | 3.2 | 3.3 | 4.0 | 3.9 | 4 | 3.6 | 3.5 | 3.6 | 3.4 | 3.5 | 3.6 |
Globulin | 2.3-4.2 mg/dL | 3.4 | 3.2 | 3.5 | 3.7 | 3.3 | 3.3 | 2.9 | 2.7 | 2.9 | 4.3 | 3.9 | 3.8 | 2.7 | 2.7 | 2.8 |
Calcium | 9-11.3 mg/dL | 10.7 | 10 | 10.9 | 10.3 | 10.1 | 9.8 | 10.2 | 10.3 | 10.9 | 12.6 | 12.6 | 12.3 | 10.7 | 10.2 | 11.9 |
Phosphorus | 2.2-6.4 mg/dL | 4.7 | 5.3 | 6.1 | 3.8 | 4 | 3.5 | 4.3 | 4.2 | 4 | 3.9 | 3.4 | 4 | 4.6 | 4.6 | 5.2 |
T. Bili | 0 – 0.4 mg/dL | 0.1 | 0.2 | 0.2 | 0.2 | 0.2 | 0.2 | 0.4 | 0.2 | 0.2 | 0.3 | 0.2 | 0.1 | 0.2 | 0.2 | 0.1 |
Sodium | 149-158 mEq/L | 150 | 147 | 148 | 149 | 147 | 147 | 145 | 146 | 146 | 148 | 147 | 149 | 151 | 151 | 149 |
Potassium | 3.7-5.3 mEq/L | 5.5 | 5.5 | 5.1 | 4.4 | 4.7 | 4.4 | 4.7 | 4.6 | 4.4 | 5.0 | 5.1 | 5.4 | 4.4 | 5 | 5.2 |
Chloride | 112-119 mEq/L | 113 | 110 | 110 | 112 | 112 | 110 | 110 | 110 | 109 | 111 | 107 | 111 | 119 | 115 | 112 |
CO2 | 15-26 mEq/L | 23.2 | 25.1 | 22.8 | 25.5 | 21 | 25.4 | 20.7 | 21.3 | 20.8 | 26.7 | 25.9 | 25.9 | 16.3 | 22.6 | 22.8 |
Anion Gap | 10-22 mEq/L | 19.3 | 17.3 | 20.3 | 15.9 | 18.7 | 11.6 | 19 | 19.3 | 20.6 | 15.3 | 19.2 | 17.5 | 20.1 | 18.4 | 18.6 |
HIL | 111 | 311 | 311 | 311 | 311 | 111 | 413 | 111 | 111 | 313 | 311 | 212 | 311 | 311 | 111 | |