Table 3 Hematologic parameters at pre-enrollment, 2 weeks after starting capecitabine, and 5 weeks after starting capecitabine. Bold numbers refer to values outside of the reference interval. Canine hematologic parameters at pre-enrollment, 2 weeks after starting capecitabine, and 5 weeks after starting capecitabine

WBC

\(4.5-16 \times 10^{3}/{\upmu }\)L

8.6

13.1

7.6

6

5.6

4.9

10.9

10.6

9.8

5.6

5.7

5.4

6.9

5.2

3.0

Bands

\(0-0.3 \times 10^{3}/{\upmu }\)L

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

Segs

\(2.8-13.4 \times 10^{3}/{\upmu }\)L

6.364

10.611

5.472

4.620

4.032

3.626

7.085

6.572

6.664

4.424

4.161

4.374

5.106

3.432

2.280

Lymphocytes

\(0.9-4 \times 10^{3}/{\upmu }\)L

1.032

0.524

0.836

0.840

0.952

0.784

2.834

3.074

2.744

0.504

0.798

0.594

0.414

0.728

0.210

Monocytes

\(0-1.3 \times 10^{3}/{\upmu }\)L

0.688

0.917

1.14

0.480

0.224

0.392

0.872

0.424

0.294

0.448

0.684

0.324

0.621

0.728

0.150

Eosinophils

\(0-1.2 \times 10^{3}/{\upmu }\)L

0.516

1.048

0.152

0.060

0.392

0.098

0.109

0.53

0.098

0.224

0.057

0.108

0.69

0.312

0.360

Basophils

\(0-0.1 \times 10^{3}/{\upmu }\)L

0

0

0

0

0

0

0

0

0

0

0

0

0.069

0.069

0.069

nRBC

\(0 /{\upmu }\)L

2

0

0

0

0

0

0

0

0

0

0

0

0

0

0

RBC

\(5.2-8.4 \times 10^{6}/{\upmu }\)L

6.79

5.68

6.18

7.55

7.65

7.36

8.090

7.89

7.75

7.43

6.7

6.18

6.61

6.65

6.71

Hemoglobin

12-20 g/dL

15.4

13

13.8

16.9

17.2

16.1

19.6

18.7

18.4

16.9

15.5

14.1

15.6

15.4

15.5

PCV

36-56%

45

40

40

49

51

46

54

52

52

50

44

41

47

46

47

MCV

62-73 fL

66

69

65

65

67

63

66

66

67

68

66

66

71

69

70

MCH

22-26 pg

23

23

22

22

22

22

24

24

24

23

23

23

24

23

23

MCHC

35-38 g/dL

34

33

34

35

34

34

36

36

36

34

35

34

33

33

33

RDW

12-15%

15

15

15

13

14

14

12

13

13

12

12

13

12

12

12

Platelets

\(160-500 \times 10^{3}/{\upmu } L\)

443

403

481

212

202

233

283

278

299

487

508

473

293

286

250

MPV

7.4-13 fL

9.4

10.2

7.9

10.8

10.9

10.1

8.2

8.8

8.2

7.9

7.8

8.5

11.1

10.7

9.7