Quality parameters Gentian CRP | ABX Pentra 400 | Abbott Architect c4000a | Olympus AU600b |
---|---|---|---|
Limit of quantification (mg/l) | 4.0c | 6,8d | 5.4e |
Linearity (mg/l) | 4–281 | 6.8–1201 | ~5–100 |
Recovery (%) | 90–105 | 116–123 | 105–118 |
No prozone effect (mg/l) | ≤ 676 | ≤ 1200 | ≤ 400 |
Precision | |||
CRP range (mg/l): | < 270; > 25 | < 270; > 25 | ≤ 100, ≥ 50 |
Intra-assay CV (%) | 0.7–1.9 | 0.5–1.7 | 1.0–1.3 |
Inter-assay CV (%) | Â | Â | Â |
- Between run CV (%) | 0.9–2.1 | 0.0–0.3 | n.d. |
- Between day CV (%) | 1.1–4.6 | 1.1–1.9 | 4.1–4.7 |
No Interference up to | |||
- Hemoglobin (g/l) | 5 | 10 | n.d. |
- Bilirubin (mg/l) | 800 | n.d. | n.d. |
- Triglycerides (g/l) | 10 | 10 | n.d. |
Method comparison | |||
Reference method | Randox Canine CRP assay | Randox Canine CRP assay | Olympus CRP |
- rs | 0.98 | 0.995 | 0.96 |
- intercept | -1.18 | 7.3 | n.d. |
- slope | 0.99 | 0.92 | n.d. |
- mean constant bias (%) | 5.2 | n.d. | 41.0–70.5f |
- TEobs (%) (~CRP 7–60 mg/l) | 9.5–20.9 | n.d. | 50.4–82.6 f |
(~CRP > 100 mg/l) | 7.0–8.9 | n.d. | n.d |
Sample type comparison | small impact | n.d. | n.d. |