Fig. 4From: The effect of intra-articular botulinum toxin A on substance P, prostaglandin E2, and tumor necrosis factor alpha in the canine osteoarthritic jointScatter plots of synovial fluid and serum pain mediators vs clinical variables of pain in osteoarthritic dogs. Synovial fluid PGE2 was found to correlate with all the three clinical variables of pain, P < 0.05. No other correlations were detected. The correlations were measured in osteoarthritic dogs at baseline. SF = synovial fluid; PGE2 = prostaglandin E2; SP = substance P; PVF = peak vertical force, VI = vertical impulseBack to article page