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Fig. 5 | BMC Veterinary Research

Fig. 5

From: Escherichia coli-derived recombinant human bone morphogenetic protein-2 combined with bone marrow-derived mesenchymal stromal cells improves bone regeneration in canine segmental ulnar defects

Fig. 5

Histology of the regenerated bone. a–f Representative histological sections of the regenerated bone at 12 weeks after surgery stained with hematoxylin and eosin (×400, scalebar = 100 μm). The groups treated with 560 μg rhBMP-2 with 107 (a), 105 (b), and 0 (c) cells, and 140 μg rhBMP-2 with 107 (d), 105 (e), and 0 (f) cells are shown. Scale bar: 500 μm. g Numbers of osteocyte-like cells per trabecular bone area. The numbers of osteocyte-like cells in the trabecular bone (mean ± SD) are shown. The numbers of osteocyte-like cells are significantly increased by transplantation with BMSCs. *P < 0.05

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