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Table 1 Clinical characteristics of the study population in the control, ACVIM B and ACVIM C groups

From: Plasma miRNAs as potential biomarkers of chronic degenerative valvular disease in Dachshunds

ACVIM stage

ACVIM A–unaffected (mean ± SD)

ACVIM B (mean ± SD)

ACVIM C (mean ± SD)

Numer of dogs

8

8

7

Age range (years)

5.458 ± 2.51

10.17 ± 3.36

10.40 ± 4.73

Sex

Males

2

4

5

Females

6

4

3

Body weight (kg)

10.38 ± 3.26

9.46 ± 2.13

9.20 ± 1.83

EF %

71.25 ± 12.26

69.5 ± 8.21

77.14 ± 3.39

LA/Ao

1.223 ± 0.10

1.479 ± 0.41

1.774 ± 0.21*

LA cm

1.938 ± 0.47

2.348 ± 0.54

2.811 ± 0.32*

LVDd

2.863 ± 0.24

2.993 ± 0.43

3.529 ± 0.42**

MVR

0

5.466 ± 1.05*** (n = 5)

5.963 ± 0.78***

RVDd

0.9375 ± 0.17

0.9275 ± 0.14

0.6057 ± 0.21**

TVR m/s

0.3988 ± 1.13

0.925 ± 1.39

2.379 ± 1.19*

  1. *statistically significant difference vs healthy dogs with p < 0.05; **statistically significant difference vs healthy dogs with p < 0.01; ***statistically significant difference vs healthy dogs with p < 0.001.