Pharmacokinetic study on pradofloxacin in the dog – Comparison of serum analysis, ultrafiltration and tissue sampling after oral administration

Table 5 Pharmakokinetik/Pharmakodynamic ratios of oral pradofloxacin values (3 mg/kg oral administration) in serum and ISF

	Pasteurella multocida(MIC₉₀= 0.015 μg/ml)		Escherichia coli(MIC₉₀= 0.03 μg/ml)		Staphylococcus pseudintermedius(MIC₉₀= 0.12 μg/ml)
	Serum	ISF	Serum	ISF	Serum	ISF
C_max/MIC₉₀	123.3	103.3	61.7	51.7	15.4	12.9
AUC_0-24/MIC₉₀	1078.7	1412.7	539.3	706.3	134.8	176.6

ISSN: 1746-6148