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Table 4 Biochemical indices of broiler-chicks infected with A. Fumigatus and treated varying doses of crude extract of Loxostylis Alata

From: A controlled study to determine the efficacy of Loxostylis alata (Anacardiaceae) in the treatment of aspergillus in a chicken (Gallus domesticus) model in comparison to ketoconazole

Serum biochemistry

Units

Dose administered (mg/kg)

  

Neutral

50

100

200

PC (60)

UC

Total serum protein (TSP)

g/l

25.52 ± 0.48

26.67 ± 0.90

28.98 ± 0.74

30.07 ± 2.26

30.90 ± 2.03

36.05 ± 9.15

Albumin (Alb)

g/l

14.33 ± 0.26

14.43 ± 0.12

15.98 ± 0.62

15.33 ± 0.39

15.90 ± 0.17

15.60 ± 0.00

Globulin (Glob)

g/L

11.19 ± 0.30

12.23 ± 0.87

13.00 ± 0.35

14.74 ± 2.34

15.00 ± 1.93

24.50 ± 9.20a

Albumin/globulin ratio (A/G)

 

1.29 ± 0.03

1.19 ± 0.09

1.23 ± 0.06

1.13 ± 0.10

1.15 ± 0.12

0.61 ± 0.43a

Calcium (Ca)

mmol/l

3.29 ± 0.10

3.42 ± 0.10

3.53 ± 0.14

3.37 ± 0.16

3.40 ± 0.10

2.92 ± 0.07

Serum inorganic phosphate (SIP)

mmol/l

1.43 ± 0.08

1.59 ± 0.10

1.60 ± 0.10

1.66 ± 0.10

1.65 ± 0.11

2.38 ± 0.96

Alanine amino transferase (ALT)

u/l

3.00 ± 0.61

3.33 ± 1.67

2.80 ± 0.97

4.86 ± 2.58

1.71 ± 0.57

1.50 ± 1.50

Aspartate amino transferase( AST)

u/l

149.20 ± 4.08

153.00 ± 8.54

138.60 ± 7.26

155.00 ± 6.24

129.43 ± 9.86

171.50 ± 22.20a

γ-glutamyltransferase (GGT)

u/l

19.60 ± 0.50

22.67 ± 0.88

23.00 ± 2.45

24.14 ± 4.12

26.57 ± 3.09

36.50 ± 17.50a

  1. Neutral group are chicks that were not infected with A. fumigatus, and were also not treated. Positive control (PC) (ketoconazole); Untreated control (UC).
  2. Means with superscript letter differ significantly (p ≤ 0.05) from the control.