Haematology | Units | Dose administered (mg/kg) | |||
---|---|---|---|---|---|
 |  | Control (DMSO ml/kg) | 50 | 200 | 300 |
Haemoglobin (Hb) | g/dl | 143.33 ± 4.7 | 139.33 ± 0.88 | 144.67 ± 8.66 | 135.50 ± 1.50 |
Red cell count (RCC) | x1012/L | 2.62 ± 0.12 | 2.50 ± 0.11 | 2.83 ± 0.09 | 2.40 ± 0.02 |
HT (haematocrit) | l/l | 0.36 ± 0.01 | 0.34 ± 0.01 | 0.33 ± 0.03 | 0.30 ± 0.01 |
Mean cell volume (MCV) | Fl | 140.00 ± 2.95 | 135.67 ± 1.77 | 126.33 ± 6.90 | 135.00 ± 1.00 |
Mean cell haemoglobin (MCH) | Pg | 54.77 ± 0.84 | 54.17 ± 0.54 | 51.40 ± 3.22 | 55.10 ± 0.35 |
Mean cell haemoglobin concentration (MCHC) | g/dl | 39.27 ± 0.23 | 39.23 ± 0.84 | 40.87 ± 0.63 | 40.90 ± 0.05 |
Red cell distribution width (RDW) |  | 13.47 ± 0.923 | 12.47 ± 0.67 | 14.77 ± 1.76 | 13.70 ± 1.15 |
White cell count (WCC) | x109/L | 3.73 ± 0.95 | 5.33 ± 1.09 | 19.80 ± 8.06a | 4.40 ± 0.80 |
Absolute neutrophil (total) | x109/L | 1.31 ± 0.26 | 1.94 ± 0.47 | 10.31 ± 4.77a | 2.30 ± 0.45 |
Absolute neutrophil (matured) | x109/L | 1.31 ± 0.26 | 1.94 ± 0.47 | 10.31 ± 4.77a | 2.30 ± 0.45 |
Absolute neutrophil (immatured) | x109/L | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 |
Absolute lymphocyte | x109/L | 1.99 ± 0.50 | 2.56 ± 0.49 | 6.25 ± 1.66a | 1.50 ± 0.34 |
Absolute monocyte | x109/L | 0.35 ± 0.15 | 0.34 ± 0.05 | 1.83 ± 1.40 | 0.40 ± 0.16 |
Absolute eosinophil | x109/L | 0.00 ± 0.00 | 0.27 ± 0.11 | 0.88 ± 0.03 | 0.1 ± 0.03 |
Absolute basophil | x109/L | 0.09 ± 0.06 | 0.07 ± 0.04 | 0.42 ± 0.02 | 0.00 ± 0.00 |