Figure 1From: Canine mesenchymal stem cells are effectively labeled with silica nanoparticles and unambiguously visualized in highly autofluorescent tissuesOptimal concentration and incubation time of silica nanoparticles for labeling of MSCs. UCBMSCs were incubated for more than 4 h with 200 or 400 μg/ml silica nanoparticles, which yielded visible fluorescent signals. However, no effective fluorescence occurred at 100 μg/ml. The majority of cells showed cytoplasmic fluorescence after 4 h of incubation. Magnification, ×400.Back to article page