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Table 2 Immunolabelling results for lymphoid tissues from sheep challenged with experimental atypical or classical scrapie

From: The natural atypical scrapie phenotype is preserved on experimental transmission and sub-passage in PRNP homologous sheep

Case number

1

2

3

4

5

18

19

20

Lateral retropharnyngeal lymph node

Neg

Neg

Neg

NA

Neg

Pos

Pos

Neg

Palatine tonsil

Neg

NA

NA

Neg

Neg

NA

NA

NA

Nictitating membrane

IT

IT

Neg

Neg

IT

Neg

IT

Neg

Spleen

Neg

Neg

Neg

Neg

Neg

Pos

Pos

Pos

Mesenteric lymph node

Neg

Neg

Neg

Neg

Neg

Pos

Pos

Pos

Distal ileum - Peyer's patches

Neg

Neg

Neg

Neg

Neg

Pos

Pos

Neg

Recto-anal mucosa associated lymphoid tissue (RAMALT)

Neg

Neg

Neg

Neg

Neg

Pos

Pos

Pos

  1. Cases 1-5: atypical scrapie.
  2. Cases 18-20: classical scrapie.
  3. Neg = Negative; Pos = Positive; IT = insufficient lymphoid tissue to test; NA = sample not available.