Figure 3

Intraneural PrP ^d accumulation in Golgi neurons of clinically affected BSE challenged deer. PrP^d immunohistochemical labelling of the cerebellar cortex using Bar 224 antibody shows accumulation in granular and molecular layers. There is prominent intraneuronal PrP^d accumulation in Golgi neurons (arrow). Linear forms of accumulation are also present, one of which is associated with a Golgi neuron cell body (brown pigment denotes PrP^d). Bar = 100 μm.