Influence of the cardiac glycoside digoxin on cardiac troponin I, acid–base and electrolyte balance, and haematobiochemical profiles in healthy donkeys (Equus asinus)

Table 2 Mean values (± standard deviation) of haematological variables in donkeys ( n = 10) injected with digoxin

Time	WBC (×10⁹/L)	Lym (×10⁹/L)	Mon (×10⁹/L)	Neu (×10⁹/L)	Eos (×10⁹/L)	Bas (×10⁹/L)	RBC (×10¹²/L)	HGB (g/dL)	HCT (%)	MCV (fl)	MCH (pg)	MCHC (g/dL)
T0	15.5 ± 4.1	4.6 ± 1.6	0.7 ± 0.4	8.2 ± 1.6	1.7 ± 1.1	0.2 ± 0.1	7.6 ± 0.3	13.3 ± 1.0	39.3 ± 3.7	51.4 ± 3.7	17.4 ± 1.1	33.9 ± 1.3
T1	16.1 ± 6.0	3.8 ± 1.7	1.0 ± 0.6	9.2 ± 3.3	1.9 ± 1.3	0.1 ± 0.1	7.4 ± 0.6	12.5 ± 1.3	37.2 ± 4.2	50.5 ± 5.0	17.0 ± 1.8	33.7 ± 1.2
T2	14.1 ± 4.0	3.5 ± 1.3	0.6 ± 0.3	8.4 ± 1.8	1.7 ± 1.2	0.2 ± 0.1	7.2 ± 0.8	12.1 ± 2.3	35.8 ± 3.9	50.7 ± 4.7	17.2 ± 1.8	33.8 ± 1.2
T3	13.3 ± 5.7	3.4 ± 1.8	0.5 ± 0.3	7.8 ± 3.0	1.7 ± 1.3	0.2 ± 0.1	6.6 ± 1.4	11.1 ± 2.2	33.5 ± 5.6	51.0 ± 4.7	17.0 ± 1.6	33.2 ± 0.9
T4	16.0 ± 4.4	3.0 ± 2.3	0.8 ± 0.4	10.6 ± 3.4	1.5 ± 1.2	0.2 ± 0.1	6.9 ± 1.9	11.7 ± 2.3	34.8 ± 5.1	51.0 ± 4.5	17.2 ± 1.5	33.7 ± 0.4
T5	16.6 ± 4.0	4.4 ± 2.1	0.7 ± 0.3	10.2 ± 3.5	1.4 ± 1.3	0.2 ± 0.1	7.3 ± 0.6	12.7 ± 1.3	37.1 ± 4.9	50.0 ± 5.1	17.3 ± 1.3	34.5 ± 1.0
T6	15.7 ± 5.3	3.4 ± 1.0	0.8 ± 0.6	9.8 ± 3.1	1.5 ± 1.2	0.2 ± 0.1	7.2 ± 0.6	12.4 ± 1.2	36.2 ± 3.8	50.0 ± 4.1	17.2 ± 1.3	34.4 ± 0.6
T7	15.9 ± 4.4	4.6 ± 1.9	0.6 ± 0.2	9.1 ± 1.9	1.7 ± 1.2	0.2 ± 0.1	7.3 ± 0.7	12.6 ± 1.2	36.5 ± 4.6	50.0 ± 4.3	17.2 ± 1.2	34.6 ± 0.9

WBC, white blood cells; Lym, lymphocyte; Mon, monocyte; Neu; neutrophil; Eos, eosinophil; Bas, Basophil; RBC, red blood cells; HGB, hemoglobin; HCT, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; PLT, platelets. T0, immediately prior to injection of digoxin; T1-T7, 1, 2, 3, 4, 24, 48 and 72 h after digoxin administration.

ISSN: 1746-6148