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Table 6 Adverse events

From: GS-9219/VDC-1101 - a prodrug of the acyclic nucleotide PMEG has antitumor activity inspontaneous canine multiple myeloma

 

Grade 1

Grade 2

Grade 3

Grade 4

Grade 5

Hypercalcemia

2*

    

Hypomagnesemia

1

    

Hypercholesterolemia

6

    

Hyperchloremia

1

    

Increased liver enzymes

5

2

1

  

Hypokalemia

3

    

Hyponatremia

3

    

Hypochloremia

3

    

Neutropenia

 

2

1

1**

 

Increased creatinine

 

1

   

Increased BUN

1

    

Hypophosphatemia

1

    

Lethargy

1

    

Anorexia

1

    

Diarrhea

1

    

Pulmonary

    

2

Dermatopathy

2

4

   
  1. *Associated with disease progression in 1 patient.
  2. **Neutropenia existed prior to treatment in this patient.
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BMC Veterinary Research

ISSN: 1746-6148

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